Results 61 to 70 of about 5,505 (208)

Biomarkers in Vestibular Schwannoma–Associated Hearing Loss

Frontiers in Neurology, 2019
Vestibular schwannomas (VSs) are benign tumors composed of differentiated neoplastic Schwann cells. They can be classified into two groups: sporadic VS and those associated with neurofibromatosis type 2 (NF2).
Luis Lassaletta, Luis Lassaletta, Luis Lassaletta, Miryam Calvino, Miryam Calvino, Jose Manuel Morales-Puebla, Pablo Lapunzina, Pablo Lapunzina, Pablo Lapunzina, Lourdes Rodriguez-de la Rosa, Lourdes Rodriguez-de la Rosa, Lourdes Rodriguez-de la Rosa, Isabel Varela-Nieto, Isabel Varela-Nieto, Isabel Varela-Nieto, Victor Martinez-Glez, Victor Martinez-Glez, Victor Martinez-Glez   +17 more
doaj   +1 more source

Mutation Spectrum and Novel Rare Variants in a Han Chinese Hearing Loss Cohort Using a Tiered Sequencing Strategy

Molecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
In a Han Chinese hearing‐loss cohort from Southwest China, a tiered strategy combining targeted hotspot screening and whole‐exome sequencing established molecular diagnoses in 25 patients, including one involving a CDH23 truncating variant not previously reported in Han Chinese patients with hearing loss, and identified a candidate SLC12A2 variant ...
Yu Zhang, Shimei Yuan, Yafang Wan, Tian Li, Lanlan Xu, Wei Yang, Changchun Niu   +6 more
wiley   +1 more source

The tympanic covering layer contributes to basilar membrane elasticity potentially influencing human frequency resolution and speech perception

Journal of Anatomy, Volume 249, Issue 3, Page 528-543, September 2026.
In this study we show for the first time that the human basilar membrane contains elastin produced by the so‐called tympanic covering layer. It is believed to play an important functional role in human cochlear tuning, particularly low frequencies linked to our remarkable speech and music perception.
Wei Liu, Claudia Steinacher, Alexander Glueckert, Rudolf Glueckert, Hao Li, Karin Staxäng, Anneliese Schrott‐Fischer, Hanif M. Ladak, Sumit Agrawal, Helge Rask‐Andersen   +9 more
wiley   +1 more source

Table_1_Detection of BDNF-Related Proteins in Human Perilymph in Patients With Hearing Loss.XLSX

, 2019
The outcome of cochlear implantation depends on multiple variables including the underlying health of the cochlea. Brain derived neurotrophic factor (BDNF) has been shown to support spiral ganglion neurons and to improve implant function in animal models.
Heike Schmitt (463610), Hinrich Staecker (6507986), Nils Prenzler (6507980), Ines de Vries (6507977), Sameer Alvi (6507983), Thomas Lenarz (491685), Martin Durisin (538612), Athanasia Warnecke (496575)   +7 more
core   +1 more source

β-trace protein (prostaglandin D synthase) - a stable and reliable protein in perilymph

GMS German Medical Science, 2005
Objective: Beta-trace protein (β-TP) has been analysed in human cerebrospinal fluid (CSF) and other body fluids. Beta-trace protein is a very sensitive and specific clinical marker and can confirm reliably the presence of CSF in patients with a suspected
Nekic, Marko, Bamborschke, Stephan, Michel, Olaf, Bachmann, Gregor   +3 more
doaj  

The Codacs™ direct acoustic cochlear implant actuator: exploring alternative stimulation sites and their stimulation efficiency. [PDF]

PLoS ONE, 2015
This work assesses the efficiency of the Codacs system actuator (Cochlear Ltd., Sydney Australia) in different inner ear stimulation modalities. Originally the actuator was intended for direct perilymph stimulation after stapedotomy using a piston ...
Martin Grossöhmichen, Rolf Salcher, Hans-Heinrich Kreipe, Thomas Lenarz, Hannes Maier   +4 more
doaj   +1 more source

Is There a Role for Sodium Fluoride in Otosclerosis Treatment?

The Laryngoscope, Volume 136, Issue 8, Page 3307-3309, August 2026.
Various reports have investigated the role of NaF for stabilizing SNHL in the setting of otosclerosis; however, there currently remains no established practice guideline or widespread consensus. The purpose of this paper is to interpret the literature to determine best practices for the use of NaF in otosclerosis management.
Timothy Shim, Kevin Wong, Michael J. Ruckenstein   +2 more
wiley   +1 more source

Data_Sheet_1_Detection of BDNF-Related Proteins in Human Perilymph in Patients With Hearing Loss.PDF

, 2019
The outcome of cochlear implantation depends on multiple variables including the underlying health of the cochlea. Brain derived neurotrophic factor (BDNF) has been shown to support spiral ganglion neurons and to improve implant function in animal models.
Heike Schmitt (463610), Hinrich Staecker (6507986), Nils Prenzler (6507980), Ines de Vries (6507977), Sameer Alvi (6507983), Thomas Lenarz (491685), Martin Durisin (538612), Athanasia Warnecke (496575)   +7 more
core   +1 more source

Labyrinthine Abnormalities on MRI in Untreated Otosclerosis: Prevalence and Clinical Relevance

The Laryngoscope, Volume 136, Issue 8, Page 3559-3568, August 2026.
In untreated otosclerosis with labyrinthine symptoms, delayed 3D FLAIR MRI rarely demonstrates endolymphatic hydrops but frequently reveals blood–labyrinth barrier (BLB) disruption. BLB enhancement is spatially associated with cochlear endosteal and round window involvement and increases with the severity of the hearing loss phenotype.
Héléna Pencroffi, Sylvain Bourdoncle, Jean Fanet, Stéphane Gargula, Denis Ayache, Loïc Duron, Julien Savatovsky, Guillaume Poillon   +7 more
wiley   +1 more source

Demographic data of the patients undergoing CI surgery with perilymph sampling and one year postoperatively audiologic test data.

, 2022
Demographic data of the patients undergoing CI surgery with perilymph sampling and one year postoperatively audiologic test data.
Heike Schmitt (463610), Caroline Krüger (10980564), Carsten Zeilinger (2120506), Nils Prenzler (6507980), Melanie Steffens (10287770), Thomas Lenarz (491685), Martin Durisin (538612), Athanasia Warnecke (496575), Andreas Pich (152212)   +8 more
core   +1 more source