Results 71 to 80 of about 5,243 (207)

A Core Head, Neck, and Neuroanatomy Syllabus for Physical Therapy Student Education

open access: yesClinical Anatomy, Volume 39, Issue 4, Page 436-460, May 2026.
ABSTRACT Head, neck, and neuroanatomy are essential components of physical therapy education due to their broad clinical applications. Detailed syllabi exist for medical students, yet none have been developed for physical therapy. This study aimed to produce an International Federation of Associations of Anatomists core head, neck, and neuroanatomy ...
Stephanie J. Woodley   +4 more
wiley   +1 more source

Advances in the Treatment of Sensorineural Hearing Loss: From Traditional Therapies to Stem Cell and Gene Therapies

open access: yesAdvanced Sensor Research, Volume 5, Issue 4, April 2026.
Sensorineural hearing loss (SNHL) occurs in 1.5 billion globally, primary driven by damage of cochlear hair cells and spiral ganglion neurons. This review systematically examines current therapeutic strategies for sensorineural hearing loss, including traditional drug and physical therapies as well as emerging stem cell and gene therapies, providing a ...
Ruirui Chen   +3 more
wiley   +1 more source

Demographic data of the patients undergoing CI surgery with perilymph sampling and one year postoperatively audiologic test data.

open access: yes, 2022
Demographic data of the patients undergoing CI surgery with perilymph sampling and one year postoperatively audiologic test data.
Heike Schmitt (463610)   +8 more
core   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

open access: yesAdvanced Science, Volume 13, Issue 20, 9 April 2026.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling   +17 more
wiley   +1 more source

Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 4, Page 712-734, April 2026.
This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang   +4 more
wiley   +1 more source

Early synapsids neurosensory diversity revealed by CT and synchrotron scanning

open access: yesThe Anatomical Record, Volume 309, Issue 4, Page 912-929, April 2026.
Abstract Non‐mammaliaform synapsids (NMS) represent the closest relatives of today's mammals among the early amniotes. Exploring their brain and nervous system is key to understanding how mammals evolved. Here, using CT and Synchrotron scanning, we document for the first time three extreme cases of neurosensory and behavioral adaptations that probe ...
J. Benoit   +6 more
wiley   +1 more source

Suspicion and Treatment of Perilymphatic Fistula: A Prospective Clinical Study

open access: yesAudiology Research
Background: Since the discovery of the perilymphatic fistula (PLF), the diagnosis and treatment remain controversial. If successfully recognized, the PLF is surgically repairable with an obliteration of the fistula site.
Issam Saliba   +2 more
doaj   +1 more source

Mannitol and the blood-labyrinth barrier

open access: yesJournal of Otolaryngology - Head and Neck Surgery, 2017
Background Characterization of the blood labyrinth barrier (BLB) is extremely important to determine whether the BLB can be manipulated pharmacologically. However, experiments to investigate the BLB are technically difficult to perform.
Trung N. Le, Brian W. Blakley
doaj   +1 more source

Evaluation of prednisolone and prednisolone sodium succinate concentrations in human plasma and inner ear perilymph during cochlear implantation 24 h after intratympanic injection

open access: yes, 2022
Background: The use of intratympanic (IT) steroids has drastically increased over the past 10-15 years to manage many otological pathologies. Objectives: This study aimed to compare the concentrations of prednisolone and prednisolone sodium succinate ...
Chiara Filippi   +6 more
core   +1 more source

Development and performance of a biomimetic artificial perilymph for in vitro testing of medical devices

open access: yes, 2019
Objective. Cochlear implants interface with the fluid in the cochlea called perilymph. The volume of this fluid present in human and animal model cochlea is prohibitively low for isolation for in vitro studies.
Palmer, JC   +7 more
core   +1 more source

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