The Effect Sodium Salicylate on Concentration of Unknown Compound in Perilymph of Guinea Pig [PDF]
There are some evidences that temporary hearing loss is induced by disturbance of cochlear microcirculation due to the inhibition of prostaglandin synthesis by salicylate, however, the mechanism of salicylate ototoxicity has been still under study ...
김혜진 +3 more
core
Introduction Traumatic perilymphatic fistula is not a rare event with regards to sport activities or traffic accident. However, iatrogenic damage to the inner ear can occur following the common use of grommets and ventilation tube insertion.
Tantely Razafimahefa Raoelina +3 more
doaj +1 more source
Is There a Role for Sodium Fluoride in Otosclerosis Treatment?
Various reports have investigated the role of NaF for stabilizing SNHL in the setting of otosclerosis; however, there currently remains no established practice guideline or widespread consensus. The purpose of this paper is to interpret the literature to determine best practices for the use of NaF in otosclerosis management.
Timothy Shim +2 more
wiley +1 more source
Labyrinthine Abnormalities on MRI in Untreated Otosclerosis: Prevalence and Clinical Relevance
In untreated otosclerosis with labyrinthine symptoms, delayed 3D FLAIR MRI rarely demonstrates endolymphatic hydrops but frequently reveals blood–labyrinth barrier (BLB) disruption. BLB enhancement is spatially associated with cochlear endosteal and round window involvement and increases with the severity of the hearing loss phenotype.
Héléna Pencroffi +7 more
wiley +1 more source
The Codacs™ direct acoustic cochlear implant actuator: exploring alternative stimulation sites and their stimulation efficiency. [PDF]
This work assesses the efficiency of the Codacs system actuator (Cochlear Ltd., Sydney Australia) in different inner ear stimulation modalities. Originally the actuator was intended for direct perilymph stimulation after stapedotomy using a piston ...
Martin Grossöhmichen +4 more
doaj +1 more source
3D‐Printed Electroanatomic Twins of Cadaveric Cochleae: A Platform for Cochlear Implant Testing
ABSTRACT Objectives Cochlear implants (CIs) can restore hearing to individuals with severe deafness, yet clinical outcomes vary widely because it remains difficult to predict how electrical currents interact with the unique anatomy of each cochlea. A central challenge in auditory rehabilitation is the lack of experimental systems that capture both the ...
Chloe Swords +7 more
wiley +1 more source
β-trace protein (prostaglandin D synthase) - a stable and reliable protein in perilymph
Objective: Beta-trace protein (β-TP) has been analysed in human cerebrospinal fluid (CSF) and other body fluids. Beta-trace protein is a very sensitive and specific clinical marker and can confirm reliably the presence of CSF in patients with a suspected
Nekic, Marko +3 more
doaj
Regional Impedance Patterns in Cochlear Implantation: Influence of Demographic and Early Activation
Implantation age is a key determinant of electrode impedance behavior, with a region‐specific effect most pronounced in the apical cochlea. Younger recipients exhibit higher intraoperative impedance followed by a time‐dependent reversal at 6 months.
Eman Hajr +4 more
wiley +1 more source
Intraspecific variation of cochlear morphology in bowhead and beluga whales
Abstract The bony labyrinth of the petrosal bone, a distinctive feature of mammal skulls, is often identified in micro‐computed tomography imaging to infer species' physiological and ecological traits. When done as part of a comparative study, one individual specimen is normally considered representative of a species, and intraspecific variation is ...
John Peacock, J. G. M. Thewissen
wiley +1 more source
AMPKα Silencing Prevents Kanamycin‐Induced Ototoxicity in an Acute Mouse Model
Kanamycin plus furosemide (KM + FU) treatment (acute ototoxic model) causes AMPKα activation and rapidly induces cochlear outer hair cell (OHC) loss. Silencing AMPKα1 via posterior semicircular canal injection 48 h before KM + FU treatment reduces this damage, preserving OHCs and hearing.
Shengyu Zou +6 more
wiley +1 more source

