Results 101 to 110 of about 4,280,016 (306)

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Perinatal mortality in the Netherlands. Backgrounds of a worsening international ranking [PDF]

Perinatal mortality rates have dropped sharply in the past few decades, in the Netherlands as well as in all other European countries. However, as the decrease has generally slowed down since the 1980s, the Netherlands has lost its prominent position in ...
Anouschka van der Meulen, Joop Garssen
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The Iowa Perinatal Letter, October, November, December 2010, Vol. 31, no. 4 [PDF]

, 2010
This newsletter from The Department of Public Health about perinatal health care and ...

core  

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Maternal postpartum six‐week check and short‐term health outcomes for women with hypertensive disorders in pregnancy: An observational study using the Clinical Practice Research Datalink (CPRD)

Acta Obstetricia et Gynecologica Scandinavica
Introduction In the UK, in addition to the recommended blood pressure check, women with hypertensive disorders of pregnancy are offered a postpartum six‐week check (SWC) with either a specialist or general practitioner.
Rema Ramakrishnan, Diane Korb, Yangmei Li, Marian Knight, Claire Carson   +4 more
doaj   +1 more source

Perinatal palliative care in Poland: current legal status, organization, standards and guidelines

Palliative Medicine in Practice
The term “perinatal hospice” as a form of targeted care for pregnant women and their families in cases of diagnosed lethal fetal anomalies first appeared in the medical literature in 1997.
Katarzyna Anna Urbańska, Anna Agnieszka Jarosz-Lesz, Magdalena Dorota Wąsek-Buko, Beata Małgorzata Naworska, Agnieszka Barbara Drosdzol-Cop   +4 more
doaj   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Perinatal care and its association with perinatal death among women attending care in three district hospitals of western Uganda

BMC Pregnancy and Childbirth
Background Provision of effective care to all women and newborns during the perinatal period is a viable strategy for achieving the Sustainable Development Goal 3 targets on reducing maternal and neonatal mortality.
Mercy Muwema, Joaniter I. Nankabirwa, Grace Edwards, Gorrette Nalwadda, Joanita Nangendo, Jaffer Okiring, Gloria Odei Obeng-Amoako, Wilson Mwanja, Elizabeth N. Ekong, Joan N. Kalyango, Dan K. Kaye   +10 more
doaj   +1 more source

The Iowa Perinatal Letter, January-February-March 2008, Vol. 29, no. 1 [PDF]

, 2008
This newsletter from The Department of Public Health about perinatal health care and ...

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Evaluation of brain development and damage using magnetic resonance imaging of congenital diaphragmatic hernia survivors: An analysis using the global brain abnormality score

Pediatrics and Neonatology
Background: The short-term prognosis of central nervous system in congenital diaphragmatic hernia (CDH) survivors has been determined by magnetic resonance imaging (MRI), but its relationship with acute management is unclear.
Tomohide Yoshida, Hideki Goya, Mayumi Tsukayama, Masaaki Kuda, Akira Yogi, Keiko Mekaru, Koichi Nakanishi   +6 more
doaj   +1 more source