Results 71 to 80 of about 109,251 (302)

Predictive value of seizure onset for gross motor dysfunction in individuals with pathogenic GABRB2 and GABRB3 variants

Epilepsia, EarlyView.
Abstract Objective Pathogenic variants in γ‐aminobutyric acid type A (GABAA) receptor genes have been associated with a wide spectrum of neurological disorders. We aimed to delineate the clinical trajectories associated with gain‐of‐function (GoF) and loss‐of‐function (LoF) variants in GABRB2 and GABRB3, and to develop a risk‐prediction model for gross
Sebastian Ortiz, Leonardo Affronte, Chiara Bagliani, Serene El‐Kamand, Anthony Sze Hon Kan, Isabel T. Kristoffersen, Rebekka S. Dahl, Anne F. Højte, Stéphane Auvin, Arjan Bouman, Shimriet Zeidler, Gerhard Kluger, Gaetan Lesca, Nicolas Chatron, Zeynep Goke‐Samar, Maria T. Papadopoulou, Matthildi Athina Papathanasiou Terzi, Elise Schaefer, Anne de Saint Martin, Sarah Baer, Mohammed Al Owain, Saud Takroni, Hesham Al‐Dhalaan, Paolo Bonanni, Alessandra Rossi, Nicoletta Zanotta, Marina Trivisano, Nicola Specchio, Angela de Dominicis, Pasquale Striano, Alessandro Orsini, Maria Margherita Mancardi, Sebastian Neuens, Melanie Jennesson‐Lyver, Ira Benkel‐Herrenbrueck, David Genevieve, Richard Sidlow, Kamer Tezcan, Ilona Krey, Johannes R. Lemke, Konrad Platzer, Damien Lederer, Inga Talvik, Ulvi Vaher, Kees P. J. Braun, Anne‐Marie Guerrot, Rebecca More, Matthias De Wachter, Sarah Weckhuysen, Evelina Carapancea, Maria Roberta Cilio, Julia Jacobs, Katalin Sterbova, Simona Balestrini, Renzo Guerrini, Giulio Peroni, Inger‐Lise Mero, Walaa ElNaggar, Nour Elkhateeb, Ariane Schmetz, Denise L. Chan, Ghayda M. Mirzaa, Boris Chaumette, Adrien Legrand, Amy McTague, Tommy Stödberg, Rebekah V. Harris, Samuel F. Berkovic, Ingrid E. Scheffer, Mary Chebib, Elena Gardella, Philip K. Ahring, Nathan L. Absalom, Rikke S. Møller   +73 more
wiley   +1 more source

Perinatal death triples the prevalence of postpartum depression among women in Northern Uganda: A community-based cross-sectional study.

PLoS ONE, 2020
IntroductionDeaths during the perinatal period remain a big challenge in Africa, with 38 deaths per 1000 pregnancies in Uganda. The consequences of these deaths can be detrimental to the women; some ending up with postpartum depression.
Anna Agnes Ojok Arach, Noeline Nakasujja, Victoria Nankabirwa, Grace Ndeezi, Juliet Kiguli, David Mukunya, Beatrice Odongkara, Vincentina Achora, Justin Bruno Tongun, Milton Wamboko Musaba, Agnes Napyo, Vivian Zalwango, Thorkild Tylleskar, James K Tumwine   +13 more
doaj   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

CAUSES AND RECURRENCE RISK OF PERINATAL LOSS

Gomal Journal of Medical Sciences, 2017
Background: Perinatal death refers to death of fetus or newborn around the time of delivery and includes both fetal deaths (at least 20 weeks of gestation) and early neonatal deaths.
Fouzia Shaikh, Sabreena Abbas, Tahira Majeed, Sajida Yousfani   +3 more
doaj  

Implementation of the Perinatal Death Surveillance and Response guidelines: Lessons from annual health system strengthening interventions in the Rwenzori Sub‐Region, Western Uganda

Nursing Open, 2020
Aim To determine the health facility‐based perinatal mortality rate, its causes and avoidable factors using the perinatal mortality surveillance and response guidelines.
Enos Mirembe Masereka, Amelia Naturinda, Alex Tumusiime, Clement Munguiko   +3 more
doaj   +1 more source

sEEG‐guided responsive neurostimulation to treat neocortical epilepsy: A multicenter retrospective study of the efficacy and safety of depth electrode‐mediated neuromodulation

Epilepsia Open, EarlyView.
Abstract Objectives Pivotal trials have established the effectiveness of the Responsive Neurostimulation System (RNS® System) in treating focal epilepsy. In clinical trials, depth leads were primarily used to treat mesial temporal seizure onsets while cortical strip leads were used to treat neocortical seizure onsets.
Sina Sadeghzadeh, David A. Purger, Priya Bhanot, Noriah Johnson, Daniel A. N. Barbosa, Yuhao Huang, Jay J. Park, Ethan Schonfeld, Matthew A. Abikenari, Bhav Jain, Joshua P. Aronson, Cornelia Drees, Tiffany L. Fisher, Jason Gerrard, Tyler E. Gray, Saadi Ghatan, Kevin Hines, Barbara C. Jobst, Ioannis Karakis, Steven G. Ojemann, Imran H. Quraishi, Ahmed M. Raslan, Michael D. Sather, Christopher T. Skidmore, Jon T. Willie, Chengyuan Wu, Ji Yeoun Yoo, Kevin D. Graber, Casey H. Halpern, Vivek P. Buch, Jonathon J. Parker   +30 more
wiley   +1 more source

From Brain Health to Brain Economy

Brain Health, EarlyView.
Yongjun Wang
wiley   +1 more source

Ultra‐refractory epilepsy: The newly described entity

Epilepsia Open, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) is defined as the failure of two antiseizure medications (ASMs) to achieve complete seizure control, affecting approximately 30% of epilepsy patients. In some cases, additional ASMs and surgical approaches are also unsuccessful.
Jan Vinklárek, Petra Búřilová, Mojdeh Raouf Zadeh, Eva Zatloukalová, Jitka Kočvarová, Ondřej Strýček, Martin Pail, Klára Štillová, Jan Chrastina, Eva Brichtová, Andrea Pokorná, Dana Mazánková, Milan Brázdil, Irena Doležalová   +13 more
wiley   +1 more source

Areas of research priorities in epilepsy: A position paper of the European Reference Network for Rare and Complex Epilepsies, EpiCARE

Epilepsia Open, EarlyView.
Abstract Objective To define and articulate research priorities in epilepsy identified by the European Reference Network for Rare and Complex Epilepsies (ERN EpiCARE), addressing key unmet needs across the spectrum of rare and complex epilepsies. Methods This position paper was developed through a structured collaborative process involving patient ...
Sébile Tchaicha, Stéphane Auvin, Sándor Beniczky, Andreas Brunklaus, Lieven Lagae, Emilio Perucca, Rainer Surges, Sophie Adler, Christoph Helmstaedter, Floor Jansen, Guido Rubboli, Philippe Ryvlin, Nicola Specchio, Eugen Trinka, Ingmar Blümcke, Valentina de Giorgis, Katarzyna Kotulska, Gaetan Lesca, Masa Malenica, Amy McTague, Rima Nabbout, Rikke Steensbjerre Møller, Sandra Silva Arrieta, Isabella Brambilla, Małgorzata Kosla, Kees Braun, J. Helen Cross, Alexis Arzimanoglou   +27 more
wiley   +1 more source

Minimum Wages, the Earned Income Tax Credit, and Mental Health Around Pregnancy

Health Economics, EarlyView.
ABSTRACT This study estimates the effects on perinatal mental health of the state's minimum wage and earned income tax credit (EITC), controlling for other policies and state‐level factors. Using data from the Pregnancy Risk Assessment Monitoring System for 2012–2018 births we find robust evidence that minimum wages and EITC levels reduce depression ...
Bryce J. Stanley, Karen Smith Conway
wiley   +1 more source