Results 81 to 90 of about 112,303 (259)
There were 841 perinatal deaths of at least 20 weeks gestation or at least 400 grams birth weight reported to the MDC in 2008. Confidential reports on 713 deaths were reviewed. Of the 585 stillbirths reported to the MDC, reviews were carried out on 487 (83.2%). The MDC was notified of 256 neonatal deaths. Reviews were carried out on 226 neonatal deaths,
openaire +1 more source
Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy
Abstract Objective In patients with drug‐resistant epilepsy who undergo anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS), efficacy is assessed months after therapy initiation and clinicians have no guidance when choosing stimulation parameters due to the lack of real‐time biomarkers.
Zachary T. Sanger +10 more
wiley +1 more source
Twin pregnancy and perinatal deaths
This is a retrospective study with the aim of revisiting twin pregnancy-a common obstetric problem-to determine if there are reductions in the incidence of very low birth weight babies, delivery problems and perinatal deaths. Three hundred and eight consecutive twin gestations were delivered at the hospital and an incidence of 21.3 per 1000 births ...
openaire +2 more sources
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are associated with high premature mortality and increased risk of sudden unexpected death in epilepsy (SUDEP). However, epidemiological data remain limited, particularly for specific syndromes such as Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), and infantile epileptic ...
Pierludovico Moro +5 more
wiley +1 more source
New insights into epileptic spasm generation and treatment from the TTX animal model
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann +2 more
wiley +1 more source
A British Pharmacological Society Position Statement on Medications in Pregnancy and Lactation
British Journal of Clinical Pharmacology, EarlyView.
Agnesa Mustafa +14 more
wiley +1 more source
Neonatal seizures and GABAergic drugs: Scylla and Charybdis?
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson +2 more
wiley +1 more source
Maternal hypertension may be an underrecognized but important risk factor for perinatal death in low resource settings. We investigated the association of maternal hypertension and perinatal mortality in rural Bangladesh.
Allyson P Bear +7 more
doaj +1 more source
Background: Perinatal death auditing is useful to identify preventable perinatal deaths and avoidable/preventable factors. Objectives: To know the impact of perinatal death audit like 1).
Harsha Kumar HN +4 more
doaj +1 more source
Abstract Objective Epilepsy affects approximately 50 million people worldwide and, although primarily attributed to neuronal dysfunction, increasing evidence highlights a critical role of glial cells, particularly astrocytes, in the pathophysiological mechanisms.
Chiara Lötzsch +5 more
wiley +1 more source

