Results 111 to 120 of about 497,285 (309)

Association of cumulative early medical events and neurodevelopmental conditions through a common latent factor—A population‐based twin study

JCPP Advances, EarlyView.
Abstract Background The cumulative effect of early medical events has been shown to be associated with autism. It is unclear whether this effect is specific to autism or if it is associated to other neurodevelopmental conditions (NDCs) as well. Methods We established a registry‐linked population‐based twin cohort of 10,254 pairs within the child and ...
Torkel Carlsson, Henrik Larsson, Sebastian Lundström, Sven Bölte, Mark J. Taylor   +4 more
wiley   +1 more source

Most costly and prevalent reasons for hospitalization in children with medical complexity in Ontario, Canada

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Children with medical complexity (CMC) have chronic health conditions often associated with functional limitations. CMC comprise 1%–5% of the pediatric population. In Canada, their care accounts for one‐third of pediatric health spending.
Erin Hessey, Thaksha Thavam, Sanjay Mahant, Eyal Cohen, Jingqin Zhu, Francine Buchanan, Teresa To, Peter J. Gill, Ontario Pediatric Hospital Care Study Group (OPHCSG) and the Canadian Paediatric Inpatient Research Network (PIRN), Wenjia Chen, Ronald Cohn, Mairead Green, Matt Hall, Kate Langrish, Colin Macarthur, Myla Moretti, Patricia Parkin, Michelle Quinlan, Ann Bayliss, Ronik Kanani, Sean Murray, Catherine Pound, Mahmoud Sakran, Anupam Sehgal, Sepi Taheri, Gita Wahi   +25 more
wiley   +1 more source

Mortalidad perinatal en el parto prematuro entre 22 y 34 semanas en un hospital público de Santiago, Chile

Revista Chilena de Obstetricia y Ginecología, 2012
Objetivo: Conocer la mortalidad perinatal del parto prematuro y los factores de riesgo asociados, usando los datos perinatales clínicos, los resultados de laboratorio y los hallazgos patológicos del feto, neonato y placenta.
Alfredo Ovalle S, Elena Kakarieka W, Marcela Díaz C, Trinidad García Huidobro M, María Jesús Acuña M, Carla Morong C, Selim Abara C, Ariel Fuentes G   +7 more
doaj  

Pre- and perinatal hypoxia associated with hippocampus/amygdala volume in bipolar disorder

Psychological Medicine, 2013
Background Pre- and perinatal adversities may increase the risk for schizophrenia and bipolar disorder. Hypoxia-related obstetric complications (OCs) are associated with brain anatomical abnormalities in schizophrenia, but their association with brain ...
U. Haukvik, Thomas F. McNeil, E. Lange, I. Melle, A. Dale, O. Andreassen, I. Agartz   +6 more
semanticscholar   +1 more source

Putamen Atrophy as a Predictive Factor of Efficacy of GPi‐DBS in Dystonia‐Dyskinesia Syndrome Secondary to Perinatal Anoxic Encephalopathy

Movement Disorders, EarlyView.
Abstract Background Perinatal hypoxic–ischemic encephalopathy (HIE) is a severe condition resulting from impaired oxygen delivery to the developing brain, often leading to both motor deficits and dystonia‐dyskinetic syndromes (DDS). In selected cases, deep brain stimulation of the globus pallidus internus (GPi‐DBS) may provide a therapeutic option ...
Marylou Grasso, Pierre‐Olivier Moser, Sidonie Sauvageot, Valérie Gil, Emilie Chan‐Seng, Emily Sanrey, Philippe Coubes, Gaëtan Poulen   +7 more
wiley   +1 more source

Melatonin and Experimental Perinatal Asphyxia

Pediatric Neurology Briefs, 2013
Researchers from University College London, Hopital Robert Debre, and Universite Paris Diderot, Paris assessed the neuroprotective effects of melatonin combined with therapeutic hypothermia after transient hypoxia-ischemia in a piglet model of perinatal ...
J. Gordon Millichap
doaj   +1 more source

Stillbirth in pregnancies with flat OGTT: Placental clues to occult maternal dysmetabolism

International Journal of Gynecology &Obstetrics, EarlyView.
Emma Bertucci, Alessandra Danieli, Francesco Ricciardiello, Isabella Neri, Francesca Monari, Alessandro D. Genazzani, Gaetano Bulfamante, Antonio La Marca, Laura Botticelli, Fabio Facchinetti, Laura Avagliano   +10 more
wiley   +1 more source

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

Glial activation in white matter following ischemia in the neonatal P7 rat brain [PDF]

, 2006
This study examines cell death and proliferation in the white matter after neonatal stroke. In post-natal day 7 injured rat, there was a marked reduction in myelin basic protein (MBP) immunostaining mainly corresponding to numerous pyknotic immature ...
Biran, Valérie, Charriaut-Marlangue, Christiane, Héron, Anne, Joly, Luc-Marie, Mariani, Jean, Renolleau, Sylvain, Vernet, Agnès, Véga, Céline   +7 more
core   +3 more sources

Neuroprotection targeting protein misfolding on chronic cerebral hypoperfusion in the context of metabolic syndrome [PDF]

, 2018
Metabolic syndrome (MetS) is a cluster of risk factors that lead to microvascular dysfunction and chronic cerebral hypoperfusion (CCH). Long-standing reduction in oxygen and energy supply leads to brain hypoxia and protein misfolding, thereby linking CCH
Capani, Francisco, Herrera, María Inés, Kusnier, Carlos Federico, Luaces, Juan Pablo, Otero-Losada, Matilde Estela, Toro Urrego, Nicolás, Udovin, Lucas   +6 more
core   +1 more source