We investigated the effects of perinatal hypoxia-ischemia (HI) on brain injury and neurological functional outcome at postnatal day (P)30 through P90. HI was induced by exposing P9 mice to 8% O2 for 55 min using the Vannucci HI model.
P. Cengiz +11 more
semanticscholar +1 more source
Perinatal Post‐Anoxic Spinal Cord Injury: A Barrier to Pallidal Neuromodulation? About 2 Cases
Movement Disorders Clinical Practice, EarlyView.
Marylou Grasso +4 more
wiley +1 more source
Gestational diabetes mellitus is associated with increased placental vascular and villous lesions compared with normoglycemic pregnancies. Distal villous immaturity was linked to adverse neonatal outcomes, while chorangiosis predicted postpartum maternal dysglycemia, highlighting the placenta as a marker of both neonatal risk and future maternal ...
Chutima Chavanisakun +2 more
wiley +1 more source
Evaluation of Pain Prevalence in Children Who Experienced Perinatal Hypoxia-Ischemia Events: Characteristics and Associations With Sociodemographic Factors. [PDF]
Von Adamovich GMG +7 more
europepmc +1 more source
ABSTRACT Aim An electrocardiogram is commonly recommended in breath‐holding spell management, mainly to rule out long QT syndrome. This retrospective study investigated the risk of long QT syndrome being misdiagnosed as breath‐holding spells in a paediatric population in southern Sweden.
Sanna Hellström Schmidt +3 more
wiley +1 more source
Early changes in cerebral metabolism after perinatal hypoxia-ischemia: a study in normothermic and hypothermic piglets. [PDF]
Andelius TCK +10 more
europepmc +1 more source
Our findings show early increased Netrin‐4 in mice with PWMI boosts angiogenesis and OPCs proliferation. Later, high levels hinder OPCs differentiation into mature cells, impairing myelination. It may act by stimulating ET‐1 secretion. Abstract Perinatal hypoxia–ischemia is a leading cause of preterm white matter injury (PWMI), yet mechanisms ...
Fuxing Dong +8 more
wiley +1 more source
Early neurodevelopmental outcome in newborns with mild hypoxic‐ischaemic encephalopathy
Aim To describe the natural history of newborn children with mild hypoxic‐ischaemic encephalopathy in the first year of life. Method This was a multicentre, prospective observational study involving five neonatal intensive care units in an Italian region using both structured clinical and neurophysiological assessments according to the Italian Society ...
Domenico M. Romeo +16 more
wiley +1 more source
Defining Longer-Term Outcomes in an Ovine Model of Moderate Perinatal Hypoxia-Ischemia. [PDF]
Mike JK +23 more
europepmc +1 more source
Epigenetic Down-Regulation of Sirt 1 via DNA Methylation and Oxidative Stress Signaling Contributes to the Gestational Diabetes Mellitus-Induced Fetal Programming of Heart Ischemia-Sensitive Phenotype in Late Life. [PDF]
Rationale: The incidence of gestational diabetes mellitus (GDM) is increasing worldwide. However, whether and how GDM exposure induces fetal programming of adult cardiac dysfunctional phenotype, especially the underlying epigenetic molecular mechanisms ...
Chen, Zewen +7 more
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