Results 181 to 190 of about 497,285 (309)

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, Volume 13, Issue 16, 18 March 2026.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

NMNAT3 is protective against the effects of neonatal cerebral hypoxia-ischemia [PDF]

, 2017
Araki, Toshiyuki, Galindo, Rafael, Greenberg, Marianne Banks, Holtzman, David M, Mehta, Nehali, Milbrandt, Jeffrey, Sasaki, Yo   +6 more
core   +2 more sources

Unraveling the role of TP53 mutations in myeloproliferative neoplasms: Molecular mechanisms of leukemic transformation

HemaSphere, Volume 10, Issue 3, March 2026.
Abstract TP53 mutations are found in over 50% of tumor types, including myeloproliferative neoplasms (MPNs). MPNs are characterized by a chronic phase, which may progress to secondary acute myeloid leukemia (sAML). Here, we discuss the physiological functions of p53 in hematopoiesis and its deregulation in MPNs.
Suzana da Silva‐Benedito, Paula Sabbo Bernardo, Jean‐Edouard Martin, Caroline Marty, Isabelle Plo, Iléana Antony‐Debré, Bárbara da Costa Reis Monte‐Mór   +6 more
wiley   +1 more source

p75NTR modulation prevents cellular, cortical activity and cognitive dysfunctions caused by perinatal hypoxia. [PDF]

Brain
Chattopadhyaya B, Lee KKY, Carreño-Muñoz MI, Paris-Rubianes A, Lavertu-Jolin M, Berryer MH, Longo FM, Di Cristo G.   +7 more
europepmc   +1 more source

Volume reduction of caudate nucleus is associated with movement coordination deficits in patients with hippocampal atrophy due to perinatal hypoxia-ischaemia. [PDF]

Neuroimage Clin, 2020
Geva S, Jentschke S, Argyropoulos GPD, Chong WK, Gadian DG, Vargha-Khadem F.   +5 more
europepmc   +1 more source

Anaemia and Maternal Iron Intakes in Pregnancy and Child Asthma: An Observational Analysis From a Longitudinal Cohort

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Evidence supporting the association between anaemia and lower iron intakes during pregnancy with an increased risk of childhood asthma remains unclear. This study aimed to investigate whether (i) lower haemoglobin or anaemia in late pregnancy and (ii) lower mean dietary iron intake in pregnancy were associated with a higher
Emma Hokey, Sophie Callanan, Anna Delahunt, Alexander Douglass, Mohammad Talaei, Seif O. Shaheen, Fionnuala M. McAuliffe   +6 more
wiley   +1 more source

The association of umbilical cord blood neurofilament light with non‐reassuring fetal status: A prospective observational study

International Journal of Gynecology &Obstetrics, Volume 172, Issue 3, Page 1491-1500, March 2026.
Abstract Objective Early detection of hypoxic–ischemic encephalopathy (HIE) in neonates is critical. We conducted a pilot cohort study to determine the feasibility of collecting umbilical cord blood samples for neurofilament light (NfL) and to assess the association of NfL with non‐reassuring fetal status and other cord biomarkers. We aimed to address (
David Zalcberg, Kaitlin Kramer, Emma Payne, Thomas Payne, Shreeya Marathe, Neha Mahajan, Ashly Liu, Jessica Barry, Andrew Duckworth, Mitchell Brooks, Bradley de Vries, Fernando Gonzalez‐Ortiz, Kaj Blennow, Henrik Zetterberg, Adrienne Gordon, Benjamin Moran, Helen J. Manning, Robert D. Sanders   +17 more
wiley   +1 more source

Perinatal Hypoxia and Immune System Activation in Schizophrenia Pathogenesis: Critical Considerations During COVID-19 Pandemic. [PDF]

Physiol Res
Kawikova I, Hakenova K, Lebedeva M, Kleteckova L, Jakob L, Spicka V, Wen L, Spaniel F, Vales K.   +8 more
europepmc   +1 more source

Is pathological fetal Doppler cerebroplacental ratio (CPR) associated with adverse delivery outcomes in pregnancies complicated by fetal growth restriction undergoing labor induction? A retrospective cohort study

International Journal of Gynecology &Obstetrics, Volume 172, Issue 3, Page 1729-1734, March 2026.
Abstract Objective The optimal delivery approach for fetal growth restriction (FGR) with pathological cerebroplacental ratio (CPR) remains uncertain. This study evaluated the association between isolated pathological CPR (<5th percentile) and delivery outcomes, specifically the rate of cesarean delivery (CD) due to non‐reassuring fetal heart rate ...
Nofar Bar Noy‐Traub, Eden Friedman, Shaked Yarza, Eynit Grinblatt, Tal Biron‐Shental, Shmuel Arnon, Michal Kovo, Dorit Ravid, Sivan Farladansky‐Gershnabel   +8 more
wiley   +1 more source

Atoh1 mediated disturbance of neuronal maturation by perinatal hypoxia induces cognitive deficits. [PDF]

Commun Biol
Cai XY, Ma SY, Tang MH, Hu L, Wu KD, Zhang Z, Zhang YQ, Lin Y, Patel N, Yang ZC, Mo XM.   +10 more
europepmc   +1 more source