Results 91 to 100 of about 2,052,438 (257)
Perinatal mortality in the Netherlands. Backgrounds of a worsening international ranking [PDF]
Perinatal mortality rates have dropped sharply in the past few decades, in the Netherlands as well as in all other European countries. However, as the decrease has generally slowed down since the 1980s, the Netherlands has lost its prominent position in ...
Anouschka van der Meulen, Joop Garssen
core
Recurrence of Preeclampsia in Northern Tanzania: A Registry-based Cohort Study. [PDF]
, 2013 Preeclampsia occurs in about 4 per cent of pregnancies worldwide, and may have particularly serious consequences for women in Africa. Studies in western countries have shown that women with preeclampsia in one pregnancy have a substantially increased ...
Lie Rolv T. +27 more
core +2 more sources
The “costly son” hypothesis: Sons exacerbate obstetrical dilemmas in humans and other mammals
The Anatomical Record, EarlyView.Abstract Human childbirth has often been considered uniquely difficult among mammals, yet recent evidence suggests that obstructed labor and fetopelvic disproportion are widespread across placental mammals. Here, we propose the “costly son” hypothesis: because male offspring are typically larger at birth, they impose greater obstetric risk on mothers ...
Nicole D. S. Grunstra +1 more
wiley +1 more source
Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Animal Research and One Health, EarlyView.Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease
Arthritis &Rheumatology, EarlyView.Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel +12 more
wiley +1 more source
Bihemispheric alterations in myelination in children following unilateral perinatal stroke
NeuroImage: Clinical, 2018 Background: Stroke is a leading cause of perinatal brain injury with variable outcomes including cerebral palsy and epilepsy. The biological processes that underlie these heterogeneous outcomes are poorly understood.
Sabrina Yu +7 more
doaj +1 more source
Two-stage approach for prediction of small-for-gestational-age neonate and adverse perinatal outcome by routine ultrasound examination at 35-37 weeks' gestation [PDF]
, 2019 Background: Justification of prenatal screening for small for gestational age (SGA) fetuses near term is based on first, evidence that such fetuses / neonates are at increased risk of stillbirth and adverse perinatal outcome, and second, the expectation ...
Ciobanu, A. +9 more
core +1 more source
Autism Research, EarlyView.ABSTRACT Exogenous prenatal exposures may affect neurodevelopment across multiple generations. We investigated grandmother and grandfather smoking, alcohol, coffee, and tea consumption during pregnancy in relation to their grandchildren's risk of autism spectrum disorder (ASD).
Michelle Pearl +6 more
wiley +1 more source
Clinical and Genetic Factors Associated With Regression in Children With Autism Spectrum Disorders
Autism Research, EarlyView.ABSTRACT Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition with complex genetic and environmental underpinnings. A clinically significant subset of children with ASD experience developmental regression (regASD), characterized by the acute loss of previously acquired skills. The mechanisms, predictors, and molecular basis of
Anna Maruani +7 more
wiley +1 more source
Sixth-Month Perinatal Outcomes of Anemic Pregnancies
Gynecology Obstetrics & Reproductive Medicine, 2014 OBJECTIVE: In this study, we retrospectively compare the outcomes of anemia in 3rd trimester pregnant women who applied to our clinic, in terms of maternal factors and its fetal effects, in 0 and 6th months.
Emel Kıyak Çağlayan +5 more
doaj