Results 101 to 110 of about 2,052,438 (257)
British Journal of Clinical Pharmacology, EarlyView.Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden +3 more
wiley +1 more source
Zuranolone: A case study in (regulatory) rush to judgement?
British Journal of Clinical Pharmacology, EarlyView.Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar +6 more
wiley +1 more source
Perinatal mortality in Ireland. Annual report 2014. [PDF]
, 2016 Perinatal mortality refers to the death of babies in the weeks before or after birth. Perinatal mortality includes stillbirths (babies born with no signs of life after 24 weeks of pregnancy or weighing at least 500 grams) and the deaths of babies within
McKernan, Joye +16 more
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British Journal of Clinical Pharmacology, EarlyView.Aim Many women take medications during pregnancy. However, the risk to the fetus from most medications is uncertain. Congenital anomalies are one of the leading causes of infant death and contribute to long‐term disability. Signal detection methods can be used to systematically identify possible medication–anomaly associations that require further ...
Hannah Johnson +22 more
wiley +1 more source
Degree and Rate of Growth Discordance in Dichorionic Twins Conceived by In Vitro Fertilization
Obstetrics and Gynecology International, 2014 Objective. Our objective was to estimate degree and rate of discordant growth and its impact on perinatal outcome in dichorionic twin pregnancies conceived by in vitro fertilization (IVF) compared to those conceived spontaneously. Study Design.
Amira S. Egic +6 more
doaj +1 more source
Brain Health, EarlyView.Epidemiology turns brain‐health evidence into action through six linked stages: characterise burden, map inequalities, identify determinants, evaluate interventions, assess implementation and value and translate evidence into policy, while maintaining data quality, equity, life‐course perspectives and stakeholder involvement.
Pierre‐Marie Preux +1 more
wiley +1 more source
Fetal macrosomia Maternal and Perinatal outcome
مجله كليه طب الكندي, 2011 Background: Fetal macrosomia represent a continuing challenge in obstetrics and increasing in it's occurrence as well as it is associated with maternal and perinatal complications.
Raida Muhammed Al - Wazzan* +1 more
doaj
Biological Reviews, EarlyView.ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino +7 more
wiley +1 more source
, 2019 This information is for anyone who wants to know about perinatal obsessivecompulsive disorder (perinatal OCD). We hope it will be helpful to: • Any woman who has, or thinks she may have, perinatal OCD • Partners, family and friends who want to find
Health Service Executive +1 more
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