Results 151 to 160 of about 10,499,951 (250)

Preparing for the European Structural Funds' next funding period [PDF]

Chapter 1 addresses central challenges (population and employment developments, innovative capacity) and highlights, in the view of the evaluators, the problem areas for the new funding period.
Ziegler, Astrid
core  

Implementing the Primary Care Behavioral Health model into routine practice in Swedish primary care: a pilot trial. [PDF]

BMC Health Serv Res
Nordgren LB, Thomas K, Ruiz ES, Koshnaw K, Fredriksson M, Nilsen P, Larsen HI.   +6 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Postoperative Complications After Lung Cancer Resection in Patients with a Previous History of Head and Neck Cancer. [PDF]

Cancers (Basel)
Falahat-Noushzady F, Herrero-Álvarez S, Molanes-López EM, Camacho-Leone R, Fraile-Olivero CA, Calatayud-Gastardi J, Jarabo-Sarceda JR, Hernando-Trancho F, Vara EM, Gómez-Martínez AM.   +9 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Data Completeness and Acceptability of Annual Feedback Reports and Tuberculosis Surveillance in Spain, 2018-2024: Mixed Methods Analysis. [PDF]

JMIR Public Health Surveill
Chatterjee A, Roy A, Amillategui R, Sastre M, Schwarz C, Cano R, Herrera-León L, Herrador Z, Spanish Working Group on Tuberculosis.   +8 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

EuroHePP: The European Toolkit to Strengthen National Responses for the Elimination of Viral Hepatitis in Prisons. [PDF]

Liver Int
Fondelli S, Arzilli G, da Costa FA, Brixko C, Butí M, Cabezas J, Cocco N, Dawson O, Deogan C, Fischer G, Komorowski A, Meroueh F, Montanari L, Mazzilli S, O'Moore É, Ranieri R, Rigoni R, Saponaro A, Seguin-Devaux C, Salah E, Seyler T, Stöver H, Tavoschi L, Duffell E.   +23 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Comparative Analysis of Metabolic and Developmental Changes Across Reproductive Stages in Breeding Pigeons. [PDF]

J Poult Sci
Ziying L, Chenjiahui Z, Rongkang Z, Huilin L, Can L, Haopeng L, Guohua T, Wuhao C, Shuangyan M, Huimin C, Xingyue Q, Yantao L, Yanhua H, Wei W, Shuo Z, Yayan L, Jie P.   +16 more
europepmc   +1 more source