Results 61 to 70 of about 922,421 (306)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti +12 more
wiley +1 more source
The Main Calculation Parameters Needed to Optimize the Thickness of the Heat Insulation in a Cooling Room of the Premises of a Cold Storage Situated in Jassy [PDF]
Bulletin of the Polytechnic Institute of Jassy: Constructions, Architechture Section, 2005 The thickness of the heat insulation optimization imposes the introduction of following parameters: a) Cooling degree-days, determinate in function of exterior air temperature and of the cooling rooms specific; b) Exploitation index which depends on the ...
Marina Verdeş +3 more
doaj
Dynamic Daylight Metrics for Electricity Savings in Offices: Window Size and Climate Smart Lighting Management [PDF]
, 2018 Daylight performance metrics provide a promising approach for the design and optimization of lighting strategies in buildings and their management.
Acosta García, Ignacio Javier +3 more
core
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego +10 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa +8 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
In Situ, 2016 Founded in 1937, the Musée national des Arts et Traditions populaires (national museum of folk art and traditions) has recently been transformed into the MuCEM, the Musée des Civilisations de l’Europe et de la Méditerranée, museum of European and ...
Bénédicte Rolland-Villemot
doaj +1 more source
How many operating rooms are needed to manage non-elective surgical cases? A Monte Carlo simulation study. [PDF]
, 2015 BackgroundPatients often wait to have urgent or emergency surgery. The number of operating rooms (ORs) needed to minimize waiting time while optimizing resources can be determined using queuing theory and computer simulation.
Antognini, Joseph F +2 more
core +3 more sources