Results 81 to 90 of about 922,421 (306)

Reduction of Clostridium Difficile and vancomycin-resistant Enterococcus contamination of environmental surfaces after an intervention to improve cleaning methods

open access: yesBMC Infectious Diseases, 2007
Background Contaminated environmental surfaces may play an important role in transmission of some healthcare-associated pathogens. In this study, we assessed the adequacy of cleaning practices in rooms of patients with Clostridium difficile-associated ...
Yadavalli Gopala K   +6 more
doaj   +1 more source

Boks w kadrze. Wybrane strategie inscenizacyjne w polskich filmach o boksie z lat sześćdziesiątych i siedemdziesiątych XX wieku

open access: yesImages, 2020
In his article, Dominik Wierski analyses and interprets selected staging strategies in Polish films about boxing. The films cited in the text were made in the 1960s and 1970s.
Dominik Wierski
doaj   +1 more source

Collapse or transformation? Regeneration and innovation at the turn of the first millennium BC at Arslantepe, Turkey [PDF]

open access: yes, 2018
Ongoing excavations at Arslantepe in south-eastern Turkey are revealing settlement continuity spanning two crucial phases at the transition from the second to the first millennium BC: the post-Hittite period and the development of Syro-Anatolian ...
DI FILIPPO, Francesco   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Penser l’histoire en acte : les period rooms dans les musées germaniques au xixe siècle

open access: yesPerspective
In the German states of the 19th century, the slow movement towards unity made history a key scholarly discipline and accorded major importance to national history, not only for scholars but for the population as a whole.
Pascal Griener
doaj   +1 more source

Exploring the Feasibility of Converting the Mardi Gras Hotel and Casino into a Casino Boutique Hotel

open access: yes, 2011
Introduction: The topic of my Professional Paper will be the feasibility study of renovating the Mardi Gras Hotel and Casino in Las Vegas, Nevada. Currently the Mardi Gras is operating as a Best Western and is looking to expand into the boutique hotel ...
Brennan, Patrick
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

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