Results 41 to 50 of about 671,343 (306)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Extension of lower and upper solutions approach for generalized nonlinear fractional boundary value problems

open access: yesArab Journal of Basic and Applied Sciences, 2022
Our main concern in this study is to present the generalized results to investigate the existence of solutions to nonlinear fractional boundary value problems (FBVPs) with generalized nonlinear boundary conditions.
Asmat Batool   +3 more
doaj   +1 more source

Continuous matrix product states with periodic boundary conditions and an application to atomtronics [PDF]

open access: yes, 2016
We introduce a time evolution algorithm for one-dimensional quantum field theories with periodic boundary conditions. This is done by applying the Dirac-Frenkel time-dependent variational principle to the set of translational invariant continuous matrix ...
D. Draxler   +3 more
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Rapid Convergence for Telegraph Systems with Periodic Boundary Conditions

open access: yesJournal of Function Spaces, 2017
The generalized quasilinearization method is applied in this paper to a telegraph system with periodic boundary conditions. We consider the case in which the forcing function F(t,x,U) satisfies the following condition: ∂n-1F(t,x,U)/∂Un-1 exists and is ...
Peiguang Wang, Xiang Liu
doaj   +1 more source

Existence of solutions for subquadratic convex or $B$-concave operator equations and applications to second order Hamiltonian systems

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2020
This paper investigates solutions for subquadratic convex or $B$-concave operator equations. First, some existence results are obtained by the index theory and the critical point theory.
Mingliang Song
doaj   +1 more source

Relation between image charge and potential alignment corrections for charged defects in periodic boundary conditions.

open access: yesJournal of Chemical Physics, 2018
Charged defects are often studied within the periodic density functional theory (DFT), but this introduces strong finite-size artifacts. In this work, we develop an electrostatic image interaction correction (IIC) method based on the direct solution of ...
T. Durrant   +5 more
semanticscholar   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Fredholm property of nonlocal problems for integro-differential hyperbolic systems

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2016
The paper concerns nonlocal time-periodic boundary value problems for first-order integro-differential hyperbolic systems with boundary inputs. The systems are subjected to integral boundary conditions.
Irina Kmit, Roman Klyuchnyk
doaj   +1 more source

Stieltjes Differential Inclusions with Periodic Boundary Conditions without Upper Semicontinuity

open access: yesMathematics, 2021
We are studying first order differential inclusions with periodic boundary conditions where the Stieltjes derivative with respect to a left-continuous non-decreasing function replaces the classical derivative.
Valeria Marraffa, Bianca Satco
doaj   +1 more source

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