Results 71 to 80 of about 285,021 (268)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

GROUP SO(4,2) AND SYMMETRY PROPERTIES OF D.I. MENDELEEV'S PERIODIC SYSTEM ELEMENTS

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
The group-based method of classification of chemical elements for definition of their place in the Mendeleev’s periodic system of elements is considered.
A. L. Gurskii, L. I. Hurski
doaj  

Group pairs with periodic cohomology

open access: yesJournal of Pure and Applied Algebra, 1990
A group pair \((G,{\mathbf S})\) with \({\mathbf S}\) a family of subgroups of \(G\) is said to be periodic if the (relative) cohomology is periodic, i.e. if there is an integer \(q\) such that for all \(k\geq 2\) and for all \(G\)-modules \(A\) one has a natural isomorphism \(H^ k(G,{\mathbf S};A)\equiv H^{k+q}(G,{\mathbf S};A)\).
BIERI, R, TALELLI, O
openaire   +3 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Generalized periodicity in group cohomology

open access: yesCommunications in Algebra, 2023
18 pages. Comments welcome!
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

On zero subrings and periodic subrings

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2001
We give new proofs of two theorems on rings in which every zero subring is finite; and we apply these theorems to obtain a necessary and sufficient condition for an infinite ring with periodic additive group to have an infinite periodic subring.
Howard E. Bell
doaj   +1 more source

Periodic elements in Garside groups

open access: yesJournal of Pure and Applied Algebra, 2011
Let $G$ be a Garside group with Garside element $ $, and let $ ^m$ be the minimal positive central power of $ $. An element $g\in G$ is said to be 'periodic' if some power of it is a power of $ $. In this paper, we study periodic elements in Garside groups and their conjugacy classes.
Lee, Eon-Kyung, Lee, Sang-Jin
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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