Results 81 to 90 of about 1,175,469 (335)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
About Periodic Shunkov Group Saturated with Finite Simple Groups of Lie Type Rank 1
Известия Иркутского государственного университета: Серия "Математика", 2016 The property of group G to be saturated with given set of groups X is a natural generalization of locally-cover definition (in class of locally finite groups) on periodic groups. Locally-finite group, witch has a locally-cover contains from finite simple
A. Shlepkin
doaj
A matched space for time scales and applications to the study on functions
Advances in Difference Equations, 2017 In this paper, using the algebraic structure of the Abelian group, we introduce the concept of a matched space for time scales, and we construct the algebraic structure of matched spaces to solve the closedness of time scales under non-translational ...
Chao Wang +2 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Armaghane Danesh Bimonthly Journal, 2020 Background & aim: Alternative training is a way to improve athletic performance. Oxidative stress caused by periodic exercise programs and pressure on the immune system may cause apoptosis and changes in Bax and Bcl-2 characteristics.
F Namani, N Abdullahzadeh
doaj
Tobacco Induced Diseases, 2011 The chest X-ray lung cancer screening program of Mayo Lung Project (MLP) yielded mixed results of improved lung case survival but no improvement in lung cancer mortality.
Lu Shi, Martin Y. Iguchi
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
GROUP SO(4,2) AND SYMMETRY PROPERTIES OF D.I. MENDELEEV'S PERIODIC SYSTEM ELEMENTS
Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019 The group-based method of classification of chemical elements for definition of their place in the Mendeleev’s periodic system of elements is considered.
A. L. Gurskii, L. I. Hurski
doaj
, 2018 We show that the presence of a non-contractible one-periodic orbit of a Hamiltonian diffeomorphism of a connected closed symplectic manifold $(M,\omega)$ implies the existence of infinitely many non-contractible simple periodic orbits, provided that the ...
Orita, Ryuma
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