Results 81 to 90 of about 6,050,140 (310)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

On Shunkov Groups Saturated with Finite Groups

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2018
The structure of the group consisting of elements of finite order depends to a large extent on the structure of the finite subgroups of the group under consideration. One of the effective conditions for investigating an infinite group containing elements
A.A. Shlepkin
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nonconstant Periodic Solutions of Discrete p-Laplacian System via Clark Duality and Computations of the Critical Groups

open access: yesAbstract and Applied Analysis, 2014
We study the existence of periodic solutions to a discrete p-Laplacian system. By using the Clark duality method and computing the critical groups, we find a simple condition that is sufficient to ensure the existence of nonconstant periodic solutions to
Bo Zheng
doaj   +1 more source

On computing normalized coprime factorizations of periodic systems [PDF]

open access: yes, 2010
A numerically reliable state space algorithm is proposed for computing normalized coprime factorizations of periodic descriptor systems. A preprocessing step is used in the algorithm to convert the initial problem for possibly non-causal systems into
Varga, Andras
core  

On Balancing and Order Reduction of Unstable Periodic Systems [PDF]

open access: yes, 2001
Abstract: We consider the direct application of balancing techniques to unstable periodic systems by extending the balancing concepts to arbitrary periodic systems. We extend first the balancing concepts to unstable discrete-time systems by defining the
A. Varga, Varga, Andras
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Uniqueness theorem for Fourier transformable measures on LCA groups

open access: yesМатематичні Студії, 2020
We show that if points of supports of two discrete ”not very thick” Fourier transformable measures on locally compact abelian (LCA) groups tend to one another at infinity and the same is true for the masses at these points, then these measures coincide ...
S.Yu. Favorov
doaj   +1 more source

Inversion-based synthesis algorithm of periodic fault detection and isolation filters [PDF]

open access: yes, 2013
A numerically reliable lifting-free computational method is proposed to solve fault detection and isolation problems for periodic systems using a model matching approach.
A. Varga, Varga, Andreas
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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