Results 91 to 100 of about 1,506,135 (383)

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

On the existence of a new type of periodic and quasi-periodic orbits for twist maps of the torus

open access: yes, 2002
We prove that for a large and important class of $C^1$ twist maps of the torus periodic and quasi-periodic orbits of a new type exist, provided that there are no rotational invariant circles (R.I.C's).
Zanata, S Addas
core   +1 more source

Linear instability of periodic orbits of free period Lagrangian systems [PDF]

open access: green, 2021
Алессандро Порталури   +2 more
openalex   +1 more source

Level spacings and periodic orbits [PDF]

open access: yesPhysical Review E, 2001
Starting from a semiclassical quantization condition based on the trace formula, we derive a periodic-orbit formula for the distribution of spacings of eigenvalues with k intermediate levels. Numerical tests verify the validity of this representation for the nearest-neighbor level spacing (k=0). In a second part, we present an asymptotic evaluation for
openaire   +3 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Existence and Uniqueness of Homoclinic Solution for a Class of Nonlinear Second-Order Differential Equations

open access: yesJournal of Applied Mathematics, 2012
The authors study the existence and uniqueness of a set with 2kT-periodic solutions for a class of second-order differential equations by using Mawhin's continuation theorem and some analysis methods, and then a unique homoclinic orbit is obtained as a ...
Lijuan Chen, Shiping Lu
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

The semiclassical relation between open trajectories and periodic orbits for the Wigner time delay

open access: yes, 2007
The Wigner time delay of a classically chaotic quantum system can be expressed semiclassically either in terms of pairs of scattering trajectories that enter and leave the system or in terms of the periodic orbits trapped inside the system.
Kuipers, Jack, Sieber, Martin
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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