Results 91 to 100 of about 645,356 (284)

Reversible Relative Periodic Orbits

Journal of Differential Equations, 2002
The aim of this paper is to extend recently obtained results [\textit{B. Sandstede}, \textit{A. Scheel} and \textit{C. Wulff}, J. Nonlinear Sci. 9, 349--378 (1999; Zbl 0951.35014); \textit{C. Wulff}, \textit{J. S. W. Lamb} and \textit{I. Melbourne}, Ergodic Theory Dyn. Syst.
Lamb, JSW, Wulff, C
openaire   +3 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Computational Methods for Periodic Systems - An Overview [PDF]

, 2001
We present an up-to-date survey of numerical methods for the analysis and design of linear discrete-time periodic systems. The basic tool is the periodic Schur form and its variants, for which a certain form of numerical stability can be ...
IFAC Workshop on Periodic Control Systems (PSYCO 2001), Dooren, Paul Van, Varga, Andras, Van Dooren, Paul   +3 more
core  

Cylindrical Manifolds and Tube Dynamics in the Restricted Three-Body Problem [PDF]

, 2004
Within the phase space of the planar circular restricted three-body problem, stable and unstable manifolds of periodic orbits with a S x R (cylindrical) geometry are shown to exist.
Ross, Shane David
core   +1 more source

Periodic orbits in outer billiard

International Mathematics Research Notices, 2006
It is shown that the set of 4-period orbits in outer billiard with piecewise smooth convex boundary has an empty interior, provided that no four corners of the boundary form a parallelogram.
Tumanov, Alexander, Zharnitsky, Vadim
openaire   +2 more sources

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Dynamical properties of maps derived from maps with strong negative Schwarzian derivative

International Journal of Mathematics and Mathematical Sciences, 1984
A strong Schwarzian derivative is defined, and it is shown that the convolution of a function with a map from an interval into itself having negative strong Schwarzian derivative is a function with negative Schwarzian derivative. Such convolutions have 0
Abraham Boyarsky
doaj   +1 more source

Control by time delayed feedback near a Hopf bifurcation point

Electronic Journal of Qualitative Theory of Differential Equations, 2017
In this paper we study the stabilization of rotating waves using time delayed feedback control. It is our aim to put some recent results in a broader context by discussing two different methods to determine the stability of the target periodic orbit in ...
Sjoerd Verduyn Lunel, Babette de Wolff
doaj   +1 more source