Results 121 to 130 of about 1,426,127 (317)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

On odd-periodic orbits in complex planar billiards

open access: yes, 2013
The famous conjecture of V.Ya.Ivrii (1978) says that {\it in every billiard with infinitely-smooth boundary in a Euclidean space the set of periodic orbits has measure zero}. In the present paper we study the complex version of Ivrii's conjecture for odd-
Glutsyuk, Alexey
core   +2 more sources

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Periodic orbits, superintegrability, and Bertrand’s theorem

open access: yesAIP Advances, 2020
Periodic orbits are the key for understanding classical Hamiltonian systems. As we show here, they are the clue for understanding Bertrand’s result relating the boundedness, flatness, and periodicity of orbits with the functional form of the potentials ...
R. P. Martínez-y-Romero   +2 more
doaj   +1 more source

Semiclassical Quantisation Using Diffractive Orbits

open access: yes, 1995
Diffraction, in the context of semiclassical mechanics, describes the manner in which quantum mechanics smooths over discontinuities in the classical mechanics.
A. Sommerfeld   +19 more
core   +2 more sources

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Solar sail trajectories at the Earth-Moon Lagrange points [PDF]

open access: yes, 2008
Paper presented during Session 3, Orbital Dynamics, Symposium C1, Astrodynamics, Paper Number 13. This paper investigates displaced periodic orbits at linear order in the circular restricted Earth-Moon system, where the third massless body is a solar ...
McInnes, Colin R., Simo, Jules
core  

Periodic orbits from nonperiodic orbits on an interval

open access: yesApplied Mathematics Letters, 1997
It is known [\textit{L. S. Block} and \textit{W. A. Coppel}, Dynamics in one dimension. Lect. Notes Math. 1513. Berlin etc.: Springer-Verlag (1992; Zbl 0746.58007)] that for a continuous function on an interval, the existence of a dense orbit implies the existence of infinitely many periodic orbits with prime periods forming an unbounded set.
Mario Martelli, Annalisa Crannell
openaire   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Periodic orbits for an autonomous version of the Duffing–Holmes oscillator

open access: yesNonlinear Analysis
In the autonomous Duffing–Holmes oscillator, the existence of periodic orbits was detected numerically. Using the Hopf bifurcation theory, we prove analytically that such periodic orbits exist.
Guangfeng Dong, Jaume Llibre
doaj   +1 more source

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