Results 111 to 120 of about 110,313 (345)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Period-Multiplying Bifurcations in the Gravitational Field of Asteroids

open access: yesAerospace
Periodic orbit families around asteroids serve as potential trajectories for space probes, mining facilities, and deep space stations. Bifurcations of these families provide additional candidate orbits for efficient trajectory design around asteroids ...
P. Rishi Krishna, Joel George Manathara
doaj   +1 more source

Extracting Multidimensional Phase Space Topology from Periodic Orbits

open access: yes, 2006
We establish a hierarchical ordering of periodic orbits in a strongly coupled multidimensional Hamiltonian system. Phase space structures can be reconstructed quantitatively from the knowledge of periodic orbits alone.
F. Gabern   +10 more
core   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Periodic Orbits with Least Period Three on the Circle

open access: yesFixed Point Theory and Applications, 2008
The self-maps on the circle having periodic orbits with least period 3 are classified into relative homotopy-conjugacy classes. We will show that except for the maps in one exceptional class, all these kinds of maps have periodic orbits with all least ...
Xuezhi Zhao
doaj   +1 more source

A dihedral Bott-type iteration formula and stability of symmetric periodic orbits [PDF]

open access: green, 2017
Xijun Hu   +2 more
openalex   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

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