Results 91 to 100 of about 110,313 (345)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
The harmonic structure of generic Kerr orbits
, 2011 Generic Kerr orbits exhibit intricate three-dimensional motion. We offer a classification scheme for these intricate orbits in terms of periodic orbits.
Grossman, Rebecca +2 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Periodic Orbits Close to That of the Moon in Hill's Problem
Frontiers in Astronomy and Space Sciences, 2018 In the framework of the restricted, circular, 3-dimensional 3-body problem Sun-Earth-Moon, Valsecchi et al. (1993) found a set of 8 periodic orbits, with duration equal to that of the Saros cycle, and differing only for the initial phases, in which the ...
Giovanni B. Valsecchi +1 more
doaj +1 more source
, 2014 Predictive Feedback Control is an easy-to-implement method to stabilize unknown unstable periodic orbits in chaotic dynamical systems. Predictive Feedback Control is severely limited because asymptotic convergence speed decreases with stronger ...
Bick, Christian +2 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
On the bifurcation and continuation of periodic orbits in the three-body problem
, 2011 We consider the planar three body problem of planetary type and we study the generation and continuation of periodic orbits and mainly of asymmetric periodic orbits. Asymmetric orbits exist in the restricted circular three body problem only in particular
Antoniadou, K. I. +2 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Benjamini-Schramm convergence of periodic orbits. [PDF]
Geom Dedic, 2022 Mohammadi A, Rafi K.
europepmc +1 more source