Results 81 to 90 of about 110,313 (345)

Marked Length Spectrum, homoclinic orbits and the geometry of open dispersing billiards

, 2019
We consider billiards obtained by removing three strictly convex obstacles satisfying the non-eclipse condition on the plane. The restriction of the dynamics to the set of non-escaping orbits is conjugated to a subshift on three symbols that provides a ...
Bálint, Péter, De Simoi, Jacopo, Kaloshin, Vadim, Leguil, Martin   +3 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Analysis and control of displaced periodic orbits in the Earth-Moon system [PDF]

, 2009
We consider displaced periodic orbits at linear order in the circular restricted Earth-Moon system, where the third massless body is a solar sail. These highly non-Keplerian orbits are achieved using an extremely small sail acceleration. In this paper we
McInnes, Colin R., Simo, Jules
core  

Semiclassical Quantisation Using Diffractive Orbits

, 1995
Diffraction, in the context of semiclassical mechanics, describes the manner in which quantum mechanics smooths over discontinuities in the classical mechanics.
A. Sommerfeld, A. Voros, B. Lauritzen, D. Ruelle, D. Ullmo, F. von Oppen, G. Date, G. Vattay, Hua Wu, J. B. Keller, M. Brack, M. C. Gutzwiller, N. D. Whelan, P. A. Dando, P. Cvitanović, P. Cvitanović, P. Exner, P. Grassberger, P. J. Richens, S. M. Reimann   +19 more
core   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Periodic orbits, superintegrability, and Bertrand’s theorem

AIP Advances, 2020
Periodic orbits are the key for understanding classical Hamiltonian systems. As we show here, they are the clue for understanding Bertrand’s result relating the boundedness, flatness, and periodicity of orbits with the functional form of the potentials ...
R. P. Martínez-y-Romero, H. N. Núñez-Yépez, A. L. Salas-Brito   +2 more
doaj   +1 more source

The structure of invariant tori in a 3D galactic potential

, 2013
We study in detail the structure of phase space in the neighborhood of stable periodic orbits in a rotating 3D potential of galactic type. We have used the color and rotation method to investigate the properties of the invariant tori in the 4D spaces of ...
Abraham R., Binney J., Contopoulos G., Contopoulos G., Contopoulos G., Froeschlé C., Froeschlé C., Kolmogorov A. N., M. KATSANIKAS, Martinet L., Miyamoto M., Moser J., P. A. PATSIS, Patsis P. A., Pfenniger D., Pfenniger D., Skokos Ch., Wiggins S., Wolfram S.   +18 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Periodic orbits for an autonomous version of the Duffing–Holmes oscillator

Nonlinear Analysis
In the autonomous Duffing–Holmes oscillator, the existence of periodic orbits was detected numerically. Using the Hopf bifurcation theory, we prove analytically that such periodic orbits exist.
Guangfeng Dong, Jaume Llibre
doaj   +1 more source

Existence of periodic orbits for geodesible vector fields on closed 3-manifolds

, 2009
In this paper we deal with the existence of periodic orbits of geodesible vector fields on closed 3-manifolds. A vector field is geodesible if there exists a Riemannian metric on the ambient manifold making its orbits geodesics.
Rechtman, Ana
core   +1 more source