Results 41 to 50 of about 1,445,125 (331)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

On a class of difference equations involving a linear map with two dimensional kernel

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2020
We establish necessary and sufficient conditions for the existence of periodic solutions to second-order nonlinear difference equations of the form $\Delta^2x_i+\lambda x_i+\Delta f(x_i)=e_i$, $i\in{\mathbb N}$, and for a simpler equation with difference-
Luís Ferreira, Luis Sanchez Rodrigues
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Displaced solar sail orbits : dynamics and applications [PDF]

open access: yes, 2010
We consider displaced periodic orbits at linear order in the circular restricted Earth-Moon system, where the third massless body is a solar sail. These highly non-Keplerian orbits are achieved using an extremely small sail acceleration.
McInnes, Colin R., Simo, Jules
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Quasi-periodic solution of quasi-linear fifth-order KdV equation

open access: yes, 2017
In this paper, we prove the existence of quasi-periodic small-amplitude solutions for quasi-linear Hamiltonian perturbation of the fifth-order KdV equation on the torus in presence of a quasi-periodic ...
Sun, Yingte, Yuan, Xiaoping
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

High-Order Melnikov Method for Time-Periodic Equations

open access: yesAdvanced Nonlinear Studies, 2017
This paper discusses a high-order Melnikov method for periodically perturbed equations. We introduce a new method to compute Mk⁢(t0){M_{k}(t_{0})} for all k≥0{k\geq 0}, among which M0⁢(t0){M_{0}(t_{0})} is the traditional Melnikov function, and M1⁢(t0 ...
Chen Fengjuan, Wang Qiudong
doaj   +1 more source

Periodic boundary value problems for first order difference equations

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2012
In this paper, existence criteria for single and multiple positive solutions of some of periodic boundary value problems for first order difference equation \[\left\{\begin{array}{ll} \Delta x(k)+f(k,x(k+1))=0, & k\in \left[ 0,T\right] ,\\ x(0)=x(T+1), &
Wen Guan, Suang-Hong Ma, Da-Bin Wang
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

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