Results 51 to 60 of about 1,447,206 (291)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Multiple periodic solutions for second order Josephson-type differential systems
Boundary Value Problems, 2017 In this paper, some new existence theorems are obtained for multiple periodic solutions of second order Josephson-type differential systems with partially periodic potential by using the minimax methods in critical point theory, which generalize and ...
Shengui Zhang
doaj +1 more source
Existence, uniqueness, and stability of periodic solutions of an equation of Duffing type
, 2007 We consider a second-order equation of Duffing type. Bounds for the derivative of the restoring force are given which ensure the existence and uniqueness of a periodic solution.
Chen, Hongbin, Li, Yi
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Averaging of Higher-Order Parabolic Equations with Periodic Coefficients
Современная математика: Фундаментальные направления, 2021 In L2(Rd;Cn), we consider a wide class of matrix elliptic operators Aε of order 2p (where p≥2) with periodic rapidly oscillating coefficients (depending on x/ε). Here ε 0 is a small parameter.
A. A. Miloslova, T. A. Suslina
doaj +1 more source
Quasi-periodic solution of quasi-linear fifth-order KdV equation
, 2017 In this paper, we prove the existence of quasi-periodic small-amplitude solutions for quasi-linear Hamiltonian perturbation of the fifth-order KdV equation on the torus in presence of a quasi-periodic ...
Sun, Yingte, Yuan, Xiaoping
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Solar sail trajectories at the Earth-Moon Lagrange points [PDF]
, 2008 Paper presented during Session 3, Orbital Dynamics, Symposium C1, Astrodynamics, Paper Number 13. This paper investigates displaced periodic orbits at linear order in the circular restricted Earth-Moon system, where the third massless body is a solar ...
McInnes, Colin R., Simo, Jules
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source