Results 51 to 60 of about 1,445,125 (331)

Multiple periodic solutions for second order Josephson-type differential systems

open access: yesBoundary Value Problems, 2017
In this paper, some new existence theorems are obtained for multiple periodic solutions of second order Josephson-type differential systems with partially periodic potential by using the minimax methods in critical point theory, which generalize and ...
Shengui Zhang
doaj   +1 more source

New periodic orbits in the solar sail restricted three body problem [PDF]

open access: yes, 2008
In this paper we consider periodic orbits of a solar sail in the Earth-Sun restricted three-body problem. In particular, we consider orbits which are high above the ecliptic plane, in contrast to the classical Halo orbits about the collinear equilibria ...
Biggs, J.D., McInnes, C., Waters, Thomas
core  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Time-periodic corner states from Floquet higher-order topology

open access: yesNature Communications, 2022
A combination of Floquet engineering and higher-order topological insulators has been lately only theoretically proposed. Here the authors experimentally realize an acoustic waveguides array to demonstrate a Floquet higherorder topological insulator ...
Weiwei Zhu   +4 more
doaj   +1 more source

Solar sail trajectories at the Earth-Moon Lagrange points [PDF]

open access: yes, 2008
Paper presented during Session 3, Orbital Dynamics, Symposium C1, Astrodynamics, Paper Number 13. This paper investigates displaced periodic orbits at linear order in the circular restricted Earth-Moon system, where the third massless body is a solar ...
McInnes, Colin R., Simo, Jules
core  

Complex periodic potentials with real band spectra

open access: yes, 1998
This paper demonstrates that complex PT-symmetric periodic potentials possess real band spectra. However, there are significant qualitative differences in the band structure for these potentials when compared with conventional real periodic potentials ...
Belokolos   +14 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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