Results 111 to 120 of about 3,975,149 (297)

Periodic Solution of a Periodic Neutral Delay Equation

Journal of Mathematical Analysis and Applications, 1997
The paper deals with the existence of positive periodic solutions of the equation \[ N'(t)= N(t)\Biggl[a(t)- \sum^n_{j= 1}b_j(t)N(t-\sigma_j)- \sum^n_{j= 1}c_j(t)N'(t-\tau_j)\Biggr],\tag{1} \] where \(a\), \(b_j\), \(c_j\), \(j= 1,2,\dots, n\) are positive continuous functions periodic with period \(\omega>0\) and \(\sigma_j\), \(\tau_j\), \(j= 1,2 ...
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Robust and minimum norm pole assignment with periodic state feedback [PDF]

, 1998
A computational approach is proposed to solve the minimum norm and/or robust pole assignment problem for linear periodic discrete-time systems. The proposed approach uses a periodic Sylvester equation based parametrization of the periodic pole ...
Varga, A.
core  

The Periodic Solutions of the Compound Singular Fractional Differential System with Delay

International Journal of Differential Equations, 2010
The paper gives sufficient conditions on the existence of periodic solution for a class of compound singular fractional differential systems with delay, involving Nishimoto fractional derivative.
XuTing Wei, XuanZhu Lu
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Remarks on periodic resonant problems with nonlinear dissipation

Electronic Journal of Differential Equations, 2021
Luis Sanchez, Joao G. Silva
doaj  

Asymptotic periodicity in nonlinear coupled matrix Sylvester Volterra systems integro-dynamic system on arbitrary time domains

Boundary Value Problems
This paper presents both a periodic and an asymptotic periodic solution for coupled Sylvester matrix Volterra integro-dynamic systems on time scales. The vectorization operator first changes the Sylvester matrix into the Kronecker product of the system ...
Chintamaneni Harisha, Bhogapurapu Venkata Appa Rao, Ayyalappagari Sreenivasulu, Ahmad Aloqaily, Maryam G. Alshehri, Nabil Mlaiki   +5 more
doaj   +1 more source

Periodic solutions of spatially periodic hamiltonian systems

Journal of Differential Equations, 1992
The existence of periodic solutions for Hamiltonian systems of ordinary differential equations (1) \(\dot z=J(H_ z(z,t)+f(t))\) is studied, where \(H: R^{2n}\times R\to R\) is of class \(C^ 1\) and is \(2\pi\)-periodic with respect to \(t\); \(f: R\to R\) is continuous and \(2\pi\)-periodic and \(J=\bigl({0 \atop I_ n} {-I_ n \atop 0}\bigr)\).
openaire   +1 more source