Results 121 to 130 of about 178,237 (295)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Periodic solutions of a class of hyperbolic equations containing a small parameter [PDF]

, 1967
Jack K. Hale
openalex   +1 more source

Periodic Solution of a Periodic Neutral Delay Equation

Journal of Mathematical Analysis and Applications, 1997
The paper deals with the existence of positive periodic solutions of the equation \[ N'(t)= N(t)\Biggl[a(t)- \sum^n_{j= 1}b_j(t)N(t-\sigma_j)- \sum^n_{j= 1}c_j(t)N'(t-\tau_j)\Biggr],\tag{1} \] where \(a\), \(b_j\), \(c_j\), \(j= 1,2,\dots, n\) are positive continuous functions periodic with period \(\omega>0\) and \(\sigma_j\), \(\tau_j\), \(j= 1,2 ...
openaire   +3 more sources

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Almost Periodic Flows and Solutions of Differential Equations [PDF]

, 1967
M. L. Cartwright
openalex   +1 more source

Theory and Applications of Periodic Solutions and Almost Periodic Solutions [PDF]

Discrete Dynamics in Nature and Society, 2013
openaire   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Periodic and almost periodic solutions for multi-valued differential equations in Banach spaces

Electronic Journal of Differential Equations, 2000
It is known that for $omega$-periodic differential equations of monotonous type, in uniformly convex Banach spaces, the existence of a bounded solution on ${Bbb R}^+$ is equivalent to the existence of an omega-periodic solution (see Haraux [5] and ...
E. Hanebaly, B. Marzouki
doaj  

Positive periodic solution for p-Laplacian neutral Rayleigh equation with singularity of attractive type. [PDF]

J Inequal Appl, 2018
Xin Y, Liu H, Cheng Z.
europepmc   +1 more source