Results 51 to 60 of about 766,070 (327)

The Lagrangian Conley Conjecture

open access: yes, 2010
We prove a Lagrangian analogue of the Conley conjecture: given a 1-periodic Tonelli Lagrangian with global flow on a closed configuration space, the associated Euler-Lagrange system has infinitely many periodic solutions.
Mazzucchelli, Marco
core   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Some Further Results on Traveling Wave Solutions for the ZK-BBM() Equations

open access: yesJournal of Applied Mathematics, 2013
We investigate the traveling wave solutions for the ZK-BBM() equations by using bifurcation method of dynamical systems. Firstly, for ZK-BBM(2, 2) equation, we obtain peakon wave, periodic peakon wave, and smooth periodic wave solutions and point out ...
Shaoyong Li, Zhengrong Liu
doaj   +1 more source

Rectangular p-periodicity and pq-periodicity of a rational difference system

open access: yesExamples and Counterexamples, 2021
In this paper, we classify periodic characters of the positive solutions of the difference system (1) xn+1=αe−(yn+xn−1)β+yn+xn−1,yn+1=γe−(xn+yn−1)δ+xn+yn−1as rectangular p-periodic and pq-periodic solutions, where the constants α,β,γ,δ,x−1,x0,y−1,y0>0 ...
D.S. Dilip, Sibi C. Babu
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Periodic solutions of periodic difference equations

open access: yesAdvanced Studies in Pure Mathematics, 2019
In this paper, we discuss the existence of periodic solutions of the periodic difference equation $$ x(n + 1) = f(n, x(n)),\ \ n \in \mathbf{Z} $$ and the periodic difference equation with finite delay $$ x(n + 1) = f(n, x_n),\ \ n \in \mathbf{Z}, $$ where $x$ and $f$ are $d$-vectors, and $\mathbf{Z}$ denotes the set of integers.
Furumochi, Tetsuo, Muraoka, Masato
openaire   +2 more sources

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Almost periodic solutions of periodic linear partial functional differential equations

open access: yes, 2018
We study conditions for the abstract periodic linear functional differential equation $\dot{x}=Ax+F(t)x_t+f(t)$ to have almost periodic with the same structure of frequencies as $f$.
Luong, Vu Trong, Van Minh, Nguyen
core   +1 more source

Periodic solutions of autonomous equations

open access: yesJournal of Mathematical Analysis and Applications, 1978
The purpose of this chapter is to give a procedure for determining periodic solutions of some classes of autonomous RFDEs.
Shui-Nee Chow, Jack K. Hale
openaire   +3 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

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