Results 71 to 80 of about 96,765 (260)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Complex network model for COVID-19: Human behavior, pseudo-periodic solutions and multiple epidemic waves. [PDF]

open access: yesJ Math Anal Appl, 2022
Silva CJ   +6 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Almost periodic processes and the existence of almost periodic solutions

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 1998
Some property which is equivalent to the concept of an asymptotically almost periodic integral for almost periodic processes is introduced. By using this property, it is shown that a precompact integral of almost periodic processes which is uniformly ...
Y. Hino, Satoru Murakami
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Variational Methods for Almost Periodic Solutions of a Class of Neutral Delay Equations

open access: yesAbstract and Applied Analysis, 2008
We provide new variational settings to study the a.p. (almost periodic) solutions of a class of nonlinear neutral delay equations. We extend Shu and Xu (2006) variational setting for periodic solutions of nonlinear neutral delay equation to the ...
M. Ayachi, J. Blot
doaj   +1 more source

A new integrable nonlocal modified KdV equation: Abundant solutions with distinct physical structures

open access: yesJournal of Ocean Engineering and Science, 2017
In this work we study a new integrable nonlocal modified Korteweg–de Vries equation (mKdV) which arises from a reduction of the AKNS scattering problem.
Abdul-Majid Wazwaz
doaj   +1 more source

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