Results 71 to 80 of about 337,853 (263)

The six stages of the convergence of the periodic system to its final structure. [PDF]

Commun Chem, 2023
Bran AM, Stadler PF, Jost J, Restrepo G.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Positive Periodic Solutions of a Periodic Discrete Competitive System Subject to Feedback Controls

Journal of Applied Mathematics, 2014
Species living in a fluctuating medium and human exploitation activities might result in the duration of continuous changes. Such changes can be well-approximated as feedback controls.
Ronghua Tan, Zuxiong Li, Qinglong Wang, Zhijun Liu   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Chaos Analysis and Synchronization Control of Coronary Artery Systems

Abstract and Applied Analysis, 2013
The present study uses the differential transformation method to solve the governing equations of the coronary artery system and then analyzes the dynamic behavior of the system by means of phase portraits, power spectra, bifurcation diagrams, and ...
Cheng-Chi Wang, Her-Terng Yau
doaj   +1 more source

A graph-theoretic method to study the existence of periodic solutions for a coupled Rayleigh system via inequality techniques

Advances in Difference Equations, 2019
In the paper, we are concerned with the existence of periodic solutions for a coupled Rayleigh system. By combining graph theory with coincidence degree theory as well as Lyapunov function method, two new sufficient conditions on the existence of ...
Zheng Zhou, Huaying Liao, Zhengqiu Zhang
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Dynamical Analysis of a Class of Prey-Predator Model with Beddington-DeAngelis Functional Response, Stochastic Perturbation, and Impulsive Toxicant Input

Complexity, 2017
A stochastic prey-predator system in a polluted environment with Beddington-DeAngelis functional response is proposed and analyzed. Firstly, for the system with white noise perturbation, by analyzing the limit system, the existence of boundary periodic ...
Feifei Bian, Wencai Zhao, Yi Song, Rong Yue   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Analysis of Periodic Orbits about the Triangular Solutions of the Restricted Sum-Jupiter and Earth-Moon Problem [PDF]

Journal of Astronomy and Space Sciences, 1988
Using the numerical solution in the plane restricted problem of three bodies, about 490 periodic orbits are computed numerically around the L5 of Sun-Jupiter and about 1600 periodic orbits also be done around the L5 of Earth-Moon system.
Sang-Young Park, Jung-Hyun Jo, Byoung-Sun Lee, Kyu-Hong Choi   +3 more
doaj