Results 151 to 160 of about 128,153 (317)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

CHARACTERIZATION OFCoRoTTARGET FIELDS WITH THE BERLIN EXOPLANET SEARCH TELESCOPE: IDENTIFICATION OF PERIODIC VARIABLE STARS IN THE LRa1 FIELD [PDF]

, 2008
P. Kábath, Philipp Eigmüller, A. Erikson, Pascal Hedelt, Philip von Paris, H. Rauer, S. Renner, R. Titz, C. Karoff   +8 more
openalex   +1 more source

Changes of Period in Variable Stars of Long Period [PDF]

Proceedings of the National Academy of Sciences, 1937
T E, Sterne, L, Campbell
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Exoplanets in the Antarctic Sky. V. The Second Data Release of AST3-II/CHESPA and Newly Found Variables within the Southern Continuous Viewing Zone of TESS

The Astrophysical Journal Supplement Series
Located at Dome A, the highest point on the Antarctic plateau, China’s Kunlun station is a premier ground-based photometric observatory. Its cold, dry, and stable atmosphere allows continuous observation for over 40 days during polar winter, ideal for ...
Bixuan Zhao, Hui Zhang, Michael C. B. Ashley, Jiapeng Zhu, Huigen Liu, Zhouyi Yu, Dan Zhou, Bin Ma, Jeremy Mould, Robert A Wittenmyer, Xiangyan Yuan, Zhengyang Li, Xiaoyan Li, Jianning Fu, Jilin Zhou, Lifan Wang   +15 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Minute-Cadence Observations of the LAMOST Fields with the TMTS: IV—Catalog of Cataclysmic Variables from the First 3-yr Survey

Universe
The Tsinghua University–Ma Huateng Telescopes for Survey (TMTS) started to monitor the LAMOST plates in 2020, leading to the discovery of numerous short-period eclipsing binaries, peculiar pulsators, flare stars, and other variable objects.
Qichun Liu, Jie Lin, Xiaofeng Wang, Zhibin Dai, Yongkang Sun, Gaobo Xi, Jun Mo, Jialian Liu, Shengyu Yan, Alexei V. Filippenko, Thomas G. Brink, Yi Yang, Kishore C. Patra, Yongzhi Cai, Zhihao Chen, Liyang Chen, Fangzhou Guo, Xiaojun Jiang, Gaici Li, Wenxiong Li, Weili Lin, Cheng Miao, Xiaoran Ma, Haowei Peng, Qiqi Xia, Danfeng Xiang, Jicheng Zhang   +26 more
doaj   +1 more source

The nature of Be stars: periodic variables in the cluster NGC 3766 [PDF]

, 1986
L. A. Balona, C. A. Engelbrecht
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source