Results 131 to 140 of about 3,822 (305)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

A Plasma Torus around a Young Low-mass Star

The Astrophysical Journal Letters
A small fraction of red dwarfs younger than ∼100 million years show structured, periodic optical light curves suggestive of transiting opaque material that corotates with the star. However, the composition, origin, and even the existence of this material
Luke G. Bouma, Moira M. Jardine
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Gaia and variable stars [PDF]

, 2017
The study of variable phenomena (periodic, irregular or transient) provides a unique way to acquire knowledge about objects in our Universe. Currently, we are going through a rapid expansion of time-domain astrophysics.
Eyer, Laurent, Holl, Berry, Mowlavi, Nami   +2 more
core  

Analysing periodic amplitude changes in RR Lyrae and other types of variable stars

, 2008
Various types of pulsating stars show periodic amplitude changes. The Fourier spectra of these stars typically exhibit a structure of either two or three close frequencies.
Breger, M., Kolenberg, Katrien, Guggenberger, E.   +2 more
core   +1 more source

K2 Photometry and Long-Term Hα Variability in Four Previously Unreported Be Stars

Universe
Classical Be stars are key laboratories for investigating how rapid rotation, pulsations, and mass loss couple to the formation and evolution of circumstellar decretion disks.
Alan Wagner Pereira, Eduardo Janot-Pacheco, Jéssica Mayara Eidam, Bergerson Van Hallen Vieira da Silva, M. Cristina Rabello-Soares, Laerte Andrade, Marcelo Emilio   +6 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Studying bright variable stars with the Multi-site All-Sky CAmeRA (MASCARA)

, 2018
Context. The Multi-site All-Sky CAmeRA (MASCARA) aims to find the brightest transiting planet systems by monitoring the full sky at magnitudes 4 < V < 8.4, taking data every 6.4 s. The northern station has been operational on La Palma since February 2015.
Burggraaff, O., I. A. G. Snellen, Snellen, I.A.G., Pollacco, D., J. Spronck, Lesage, A.-L., V. Van Eylen, Spronck, J., Otten, G.P.P.L., R. Stuik, Stuik, R., O. Burggraaff, Van Eylen, V., G. P. P. L. Otten, A.-L. Lesage, Talens, G.J.J., G. J. J. Talens, D. Pollacco   +17 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source