Results 131 to 140 of about 72,602 (290)

K2 Photometry and Long-Term Hα Variability in Four Previously Unreported Be Stars

open access: yesUniverse
Classical Be stars are key laboratories for investigating how rapid rotation, pulsations, and mass loss couple to the formation and evolution of circumstellar decretion disks.
Alan Wagner Pereira   +6 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Exoplanets in the Antarctic Sky. V. The Second Data Release of AST3-II/CHESPA and Newly Found Variables within the Southern Continuous Viewing Zone of TESS

open access: yesThe Astrophysical Journal Supplement Series
Located at Dome A, the highest point on the Antarctic plateau, China’s Kunlun station is a premier ground-based photometric observatory. Its cold, dry, and stable atmosphere allows continuous observation for over 40 days during polar winter, ideal for ...
Bixuan Zhao   +15 more
doaj   +1 more source

Irregularities of Period of Long-Period Variable Stars [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 1929
A. S. Eddington, S. Plakidis
openaire   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Quadruple system HD 135160 in a unique 2+2 configuration

open access: yesAstronomy & Astrophysics
Analysing a large body of observational data, we found that HD 135160 is a quadruple 2+2 system, composed of a massive ellipsoidal binary (‘heartbeat’ star) with components Aa and Ab in an eccentric 8.234 d orbit and an eclipsing binary (with components ...
Zummer M.   +4 more
doaj   +1 more source

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