Results 111 to 120 of about 3,995 (217)

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

Hesperidin and Its Polylactic-<i>co</i>-glycolic Acid-Nanoformulation Mitigate Rhabdomyolysis-Induced Acute Kidney Injury via Attenuation of Oxidative Stress and Inflammation in BALB/c Mice. [PDF]

ACS Omega
Borges KJJ, Wasim B, Hameed A, Yasmeen T, Shah MR, Jabri T, Rao K, Ahmed J.   +7 more
europepmc   +1 more source

Joint universality of zeta-functions with periodic coefficients

, 2012
Darbe yra įrodomas jungtinis universalumas periodinėms Hurvico dzeta funkcijoms, taip pat bendras universalumas su Rymano dzeta funkcija ir normuotų parabolinių formų dzeta funkcija.
openaire   +2 more sources

NIR‐Activatable Domino Cascade Catalysis Nanozyme Reactor for Multi‐Mechanism Synergistic Immunotherapy in Bladder Cancer

Advanced Science, EarlyView.
This study presents an intravesical delivery strategy of ferroptosis‐ and immunity‐inducing nanozyme‐loaded thermoresponsive hydrogels (FMCC@PNH) for enhanced bladder cancer therapy. Abstract Current intravesical therapies for bladder cancer after resection are limited by poor tissue penetration, off‐target effects, and insufficient efficacy.
Yongnan Jiang, Qingling Zhang, Yuhan Zhang, Xinlu Yu, Bo Jia, Yulong Dong, Yalong Wu, Kelong Fan, Xinquan Gu, Lei Ji, Wei Jiang, Bin Liu   +11 more
wiley   +1 more source

Ionic surfactants alter virus surface properties and electrostatic interactions in aqueous systems. [PDF]

FEMS Microbes
Loey M, Da Hora GCA, Weidhaas J.
europepmc   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Ab Initio Molecular Dynamics Study of Quadrupolar Spin Relaxation in an Ionic Liquid. [PDF]

J Comput Chem
Vidal LN, Ducati LC, Autschbach J.
europepmc   +1 more source

Value distribution theorems for the periodic zeta-function

, 2010
Darbe nagrinėjama periodinės dzeta funkcijos antrojo momento liekamojo nario išreikštinis pavidalas ir šios funkcijos asimptotinio elgesio charakterizacija ribinių teoremų silpnojo tikimybinių matų konvergavimo prasmė įvairiose erdvėse pagalba. Darbo uždaviniai yra šie: 1. Įrodyti Atkinsono formulę periodinai dzeta funkcijai kritinėje tiesėje.
openaire   +2 more sources

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source

Charge-Programmable Alternating Copolymers via Self-Catalyzed Aqueous Polymerization for Tunable Bacterial Translocation and Macrophage Polarization. [PDF]

JACS Au
Wang X, Huang R, Li J, Zhu Y, Zhu Z, Rao J.   +5 more
europepmc   +1 more source