Results 41 to 50 of about 30,432 (264)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

The Assessment of Iranian Systematic Review Articles in Biomedical Sciences Based on the Scientometrics Methods

open access: yesمدیریت اطلاعات سلامت, 2019
Introduction: Studying the growth of scientific outputs in different subject areas can be one of the foundations of scientific policymaking in that field.
Sornaz Shadi   +2 more
doaj   +1 more source

LAUNCHING UKRAINIAN COUNCIL OF SCIENCE EDITORS AND EDUCATING REGIONAL JOURNAL EDITORS

open access: yesProceedings of the Shevchenko Scientific Society: Medical Sciences, 2020
Global editorial associations have accumulated knowledge and resources that could be helpful for emerging editors groups and societies. Increasing awareness of and enforcing the available editorial recommendations is essential for improving the quality ...
Olena Zimba   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Emerging concepts in high-impact publishing: insights from the First Brazilian Colloquium on High Impact Research and Publishing

open access: yesAnnali dell'Istituto Superiore di Sanità
Reports of scientific research are published by selective journals only when they meet stringent criteria, first and foremost of which are the quality and importance of the research.
Valerie Matarese
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

SOCIAL MEDIA FOR MEDICAL JOURNALS

open access: yesCentral Asian Journal of Medical Hypotheses and Ethics, 2020
Social networks are now an integrated part of life in most digitally connected societies. Bringing scientific papers of interest to a defined audience using the appropriate channel might substantially contribute to the impact of a scientific discovery ...
Sakir Ahmed, Latika Gupta
doaj   +1 more source

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