Results 51 to 60 of about 28,993 (266)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Emerging concepts in high-impact publishing: insights from the First Brazilian Colloquium on High Impact Research and Publishing

open access: yesAnnali dell'Istituto Superiore di Sanità
Reports of scientific research are published by selective journals only when they meet stringent criteria, first and foremost of which are the quality and importance of the research.
Valerie Matarese
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Clarity in medical writing

open access: yesSouthwest Respiratory and Critical Care Chronicles, 2015
Clarity is the most significant aspect of medical writing. This article explains the importance of clarity and offers practical advice for writing clearly at the language and sentence levels.
Kristin Messuri
doaj  

SOCIAL MEDIA FOR MEDICAL JOURNALS

open access: yesCentral Asian Journal of Medical Hypotheses and Ethics, 2020
Social networks are now an integrated part of life in most digitally connected societies. Bringing scientific papers of interest to a defined audience using the appropriate channel might substantially contribute to the impact of a scientific discovery ...
Sakir Ahmed, Latika Gupta
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Choosing and using verbs

open access: yesSouthwest Respiratory and Critical Care Chronicles, 2016
Choosing precise, vivid verbs improves the clarity and enhances the style of medical writing. Ideally, writers should use precise, vivid verbs in medical writing and other genres.
Kristin Messuri
doaj  

The First Fifty Years of the Journal Acta Stomatologica Croatica (1966 - 2016): Citation Analysis

open access: yesActa Stomatologica Croatica, 2018
Acta Stomatologica Croatica (ASCRO) citation analysis was made on the occasion of fifty years of publishing the journal (1966 to 2016). The aim of the study was to determine the impact of the changes that have been occurring over the last ten years on ...
Vesna Borić, Lidija Štefić
doaj   +1 more source

Structural Classification of Topic Sentences in Chinese of Different Periods

open access: yesPhilology. Theory & Practice, 2022
The study aims to develop a comparative classification of topic sentences in early classical Archaic Chinese (the V-III centuries BC), late Literary Chinese (the late XVII - the early XVIII century) and modern Chinese. Scientific novelty of the study is accounted for by the fact that the classification of topic sentences is created based on the ...
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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