Results 81 to 90 of about 133,608 (290)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer   +11 more
wiley   +1 more source

Consecutive Power Occurrences in Sturmian Words

open access: yesComptes Rendus. Mathématique
We show that every Sturmian word has the property that the distance between consecutive ending positions of cubes occurring in the word is always bounded by $10$ and this bound is optimal, extending a result of Rampersad, who proved that the bound $9 ...
Bell, Jason   +2 more
doaj   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

Sazonalidade em séries temporals quadrissemanais — o caso do IMEC

open access: yesEconomia Aplicada, 1999
This paper uses the available econometric techniques to analyze the seasonality in the time series of the Indicator of Economic Movements (IMEC), measured by Fundayao Instituto de Pesquisas Economicas (PIPE), from Sao Paulo (Brazil).
Eliezer Martins Diniz
doaj  

Study on the Water Volume of Erhai Lake in Yunnan Plateau

open access: yesRenmin Zhujiang, 2021
Based on the monitoring results of hydrological factors such as measured discharge,precipitation,evaporation and outflow in the Erhai Lake Basin from 1956 to 2018,this paper calculates the natural water volume of the Erhai Lake by using two related ...
LI Hongyan
doaj  

On horadam sequence periodicity: A new approach [PDF]

open access: yes, 2015
A so called Horadam sequence is one delivered by a general second\ud order recurrence formula with arbitrary initial conditions.\ud We examine aspects of self-repeating Horadam sequences by\ud applying matrix based methods in new ways, and derive some ...
Larcombe, Peter J., Fennessey, Eric J.
core  

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

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