Results 61 to 70 of about 136,735 (253)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Distribution of histopathological types of thyroid tumors in 1999-2015 compared to 1966-1988 year period [PDF]

open access: yesArchive of Oncology, 2020
Background: The most common thyroid tumors originate from the epithelial follicular cells. Etiology involved in the development of thyroid carcinoma is multifactorial, including external influences and genetic predisposition.
Makazlieva Tanja   +3 more
doaj  

Influence of atmospheric pressure change on gas sampling in mine closed area

open access: yes矿业科学学报, 2020
The variation of atmospheric pressure will cause the exchange of air volume between the closed area of the mine and the external environment, which will have an impact on the gas migration in the closed area of the mine.In order to study the influence of
Lei Baiwei   +3 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Common intraday periodicity [PDF]

open access: yes
Using a reduced rank regression framework as well as information criteria we investigate the presence of commonalities in the intraday periodicity, a dominant feature in the return volatility of most intraday financial time series.
Palm Franz   +2 more
core  

Pure point diffraction and almost periodicity [PDF]

open access: yes, 2023
This article deals with pure point diffraction and its connection to various notions of almost periodicity. We explain why the Fibonacci chain does not fit into the classical class of Bohr almost periodicity and how it fits into the classes of mean ...
Spindeler, Timo   +2 more
core   +1 more source

Applicability Analysis of InSAR Tropospheric Delay Correction for Landslide Monitoring Considering Periodicity Characteristics—Case Study on Southwest Mountainous Region

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Tropospheric delay is a major limitation in interferometric synthetic aperture radar (InSAR) for measuring landslide deformation. It exhibits complex spatial–temporal variability, stochastic behavior, and is particularly difficult to model in the ...
Li Zhang   +8 more
doaj   +1 more source

Effect of Latitude on Seasonality of Tuberculosis, Australia, 2002–2011

open access: yesEmerging Infectious Diseases, 2012
Seasonal variation in tuberculosis diagnoses recently has been reported in various populations. In Australia, seasonality of tuberculosis diagnoses was more pronounced in areas where UV exposure is reduced and vitamin D deficiency is more prevalent.
Jennifer H. MacLachlan   +2 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Robust estimation of intraweek periodicity in volatility and jump detection. [PDF]

open access: yes
Opening, lunch and closing of financial markets induce a periodic component in the volatility of high-frequency returns. We propose a non-parametric weighted standard deviation and parametric truncated maximum likelihood estimation procedure for the ...
Croux, Christophe   +2 more
core  

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