Results 51 to 60 of about 136,735 (253)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Seasonal variation in the month of first visit for atopic dermatitis patients

open access: yesAllergology International, 1998
The total number of new attendant patients diagnosed as having atopic dermatitis at our dermatology outpatient clinic during the 7 year period from 1989 to 1995 was 10 156.
Toshiyuki Aoki   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Periodicity of DNA in Exons [PDF]

open access: yes, 2008
BACKGROUND: The periodic pattern of DNA in exons is a known phenomenon. It was suggested that one of the initial causes of periodicity could be the universal (RNY)npattern (R = A or G, Y= C or U, N = any base) of ancient RNA.
Eskesen, ST   +3 more
core   +1 more source

Periodicity of Degenerate Strings

open access: yes, 2023
Estéban Gabory, Eric Rivals, Michelle Sweering, Hilde Verbeek, Pengfei Wang: Periodicity of Degenerate Strings, pp. 42–56.Czech Technical University in Prague, Czech RepublicProceedings of PSC 2023, Jan Holub and Jan Žd’árek (Eds.), ISBN 978-80-01-07206 ...
Sweering, Michelle   +4 more
core   +2 more sources

GPS Time Series Analysis from Aboa the Finnish Antarctic Research Station

open access: yesRemote Sensing, 2018
Continuous Global Positioning System (GPS) observations have been logged at the Finnish Antarctic research station (Aboa) since February 2003. The station is located in Dronning Maud Land, East Antarctica.
Constantin-Octavian Andrei   +6 more
doaj   +1 more source

Evidence for Solar Modulation on the Millennial-Scale Climate Change of Earth

open access: yesUniverse, 2020
In this study, we use available reconstructed data to investigate periodicities of solar activity (i.e., sunspot number) and the Earth’s climate change (temperatures of Lake Qinghai in China and Vostok in Antarctica, the GISP δ18O climate record of ...
Xinhua Zhao   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

The chronobiology of migraine: a systematic review

open access: yesThe Journal of Headache and Pain, 2021
Background The paroxysmal nature of migraine is a hallmark of the disease. Some patients report increased attack frequency at certain seasons or towards the end of the week, while others experience diurnal variations of migraine attack onset.
Amanda Holmen Poulsen   +3 more
doaj   +1 more source

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