Results 121 to 130 of about 433,738 (330)

Art history: formation of the academic discipline in Europe, and related developments in Greece (18th-19th c.) Rethymnon (3-4 October, 2014) [PDF]

open access: yesJournal of Art Historiography, 2015
The Academic Forum with the title Art history: formation of the academic discipline in Europe and related developments in Greece (18th-19th centuries), co-organised by the Association of Greek Art Historians and the Institute for Mediterranean Studies ...
Annie Malama
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

CYCLICAL DYNAMICS OF TRANSPORT PRICING POLICY

open access: yesВестник университета, 2019
The article presents a periodization of the transport pricing policy in Russia, taking into account the dynamic properties of the world-system economic processes. The analysis of the main approaches to the periodization of the transport pricing policy is
T. Gainochenko
doaj  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Periodic twisted cohomology and T-duality

open access: yes, 2010
The initial motivation of this work was to give a topological interpretation of two-periodic twisted de-Rham cohomology which is generalizable to arbitrary coefficients.
Bunke, Ulrich   +2 more
core  

Formation of the <0001>-Rotation-Type Kink Boundary in an Extruded Mg-Zn-Y Alloy of Long-Period Stacking Ordered Structure

open access: green, 2020
Michiaki Yamasaki   +5 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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