Results 121 to 130 of about 48,314 (295)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Periodization approaches of capitalist development: A critical survey [PDF]
Business ...
Pennavaja, C.
core +1 more source
Some Results on Study of The Oroshayemoye Site in the Steppe Zone of the Volga Region
Археология евразийских степейNeolithic-Eneolithic sites in the steppe zone are not so many. Therefore, new settlement excavations are very important. One of them is the Oroshayemoye settlement.
Aleksander A. Vybornov +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Periodization and Chronology of the Neolithic Upper Sukhona and Eastern Lake Onega Region
Археология евразийских степейThe river network of the Vologda region is very dense and belongs to three basins: the White, Baltic and Caspian seas. This fact affects the cultural and historical development of different areas of the Vologda region already in ancient times.
Nadezhda G. Nedomolkina
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
I.M. Reisner: The periodization of the New History of the East
RUDN Journal of World History, 2013 The article is a publication of the material associated with the scientific work of the outstanding Russian orientalist I.M. Reisner. Published manuscript is written with the hand of I.M. Reisner.
A A Kudelin
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