Results 81 to 90 of about 48,314 (295)
Origin and Development of Higher Professional Education System in Russia: Problem of Periodization
Научный диалог, 2018 The article is devoted to the subject insufficiently developed in the national historiography. The purpose of writing this work was to study the problem of periodization of the history of higher education system (HPES) in Russia.
V. N. Mamyachenkov
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Key Dates in the History of the Kyiv-Mohyla Academy
Kyiv-Mohyla Humanities Journal, 2015 The researchers of the Kyiv-Mohyla Academy of the 19th and the beginning of the 20th centuries defined its periodization and the important dates in its history.
Maksym Iaremenko
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Sampling and reconstruction of operators
, 2015 We study the recovery of operators with bandlimited Kohn-Nirenberg symbol from the action of such operators on a weighted impulse train, a procedure we refer to as operator sampling.
Pfander, Götz E., Walnut, David F.
core +1 more source
Этапы становления академической музыкальной культуры в Енисейской губернии: вопросы периодизации
Вестник музыкальной науки, 2019 Статья посвящена краеугольной проблеме генезиса академической музыкальной культуры Енисейской губернии - периодизации данного процесса. До настоящего времени не было создано научного труда, специально и комплексно освещающего историю музыкальной культуры
Царёва, Евгения Сергеевна
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source