Results 91 to 100 of about 48,314 (295)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Periodization and its discontents [PDF]
Journal of Art Historiography, 2010 This essay originated as an editorial for an issue of Perspective devoted to periodization. It traces the critique and dismantling of this conception in art history, and argues that even most recent literature suggests that the problematic of ...
Thomas DaCosta Kaufmann
doaj
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Structuring of the periodization in antiquity: the Roman military training
Tanjungpura Journal of Coaching ResearchBackground and Study Aim. The sportive periodization originated from the military periodization of ancient civilizations and of the Greek Tetrad for the sportive preparation the ancient Greek athletes.
Nelson Kautzner Marques Junior
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Solving the Boltzmann equation in N log N
, 2006 In [C. Mouhot and L. Pareschi, "Fast algorithms for computing the Boltzmann collision operator," Math. Comp., to appear; C. Mouhot and L. Pareschi, C. R. Math. Acad. Sci. Paris, 339 (2004), pp.
Bird G. +9 more
core +4 more sources
ON THE ISSUE OF RE-EVACUATION PROCESS PERIODIZATION
Вестник Кемеровского государственного университета, 2015 The subject of the research is the re-evacuation process. The purpose of the paper is to set forth and substantiate the author’s view of a very important and problematical component of the re-evacuation process – its periodization.
L. I. Snegireva
doaj
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Frontiers in Physiology, 2019 Periodization schedules training periods according to predicted timings of cumulative adaptations and has been at the foundation of exercise prescription.
José Afonso +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source