Results 141 to 150 of about 199,048 (383)

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Bayesian Nonparametric Policy Search with Application to Periodontal Recall Intervals [PDF]

arXiv, 2018
Tooth loss from periodontal disease is a major public health burden in the United States. Standard clinical practice is to recommend a dental visit every six months; however, this practice is not evidence-based, and poor dental outcomes and increasing dental insurance premiums indicate room for improvement.
arxiv  

In situ biomimetic materials for dentin repair

BMEMat, EarlyView.
This review primarily discusses the role and clinical application of key biomimetic materials for in situ dentin repair, providing a feasible foundation for future material and performance optimization in situ dentin regeneration. Abstract Dental defects, ranking among the most prevalent diseases globally, pose a serious threat to human health, with ...
Jingjing Deng, Siyi Ren, Xuliang Deng, Yan Wei   +3 more
wiley   +1 more source

Can oral infection be a risk factor for Alzheimer’s disease? [PDF]

, 2015
Alzheimer’s disease (AD) is a scourge of longevity that will drain enormous resources from public health budgets in the future. Currently, there is no diagnostic biomarker and/or treatment for this most common form of dementia in humans.
Alzheimer A, Ball MJ, Bünzli D, Cicci[ugrave] M, Dunn N, Hachinsky V, Ingar Olsen, Kovács T, Lin WR, Miklossy J, Mori I, Oldfield BJ, Ouerfurth HW, Regitz C, Sim K. Singhrao, Song Y, Urovesic N, Whittum-Hudson JA   +17 more
core   +2 more sources

Validity of Simple Self-Reported Periodontal Status Questions

International Dental Journal, 2023
: Objective: The aim of this research was to evaluate the validity of the questions developed by Thai periodontists on self-reported periodontal status and symptoms in identifying severe periodontitis amongst adults in Thailand.
Attawood Lertpimonchai, Supang Tuntrakul, Sasivimol Rattanasiri, Pimchanok Sutthiboonyapan, Prin Vathesatogkit, Artit Udomsak, Kanoknadda Tavedhikul   +6 more
doaj  

Expertise‐inspired artificial intelligence pipeline for clinically applicable reconstruction of tooth‐centric radial planes: Development and multicenter validation

BMEMat, EarlyView.
The expertise‐inspired AI pipeline demonstrates significant clinical utility for rapid and precise analysis of dento‐maxillofafcial CBCT and benefits for intelligent oral health management. Abstract Owing to the tooth‐centered nature of most oral diseases, the tooth‐centric radial plane of cone‐beam computed tomography (CBCT) depicts the anatomical and
Zhuohong Gong, Gengbin Cai, Jiayang Zeng, Beichen Wen, Hengyi Liu, Jiahong Lin, Xiaofei Meng, Peisheng Zeng, Jiamin Shi, Rui Xie, Yang Yu, Yin Xiao, Mengru Shi, Ruixuan Wang, Zetao Chen   +14 more
wiley   +1 more source

Gene Therapy Using Recombinant AAV Type 8 Vector Encoding TNAP‐D10 Improves the Skeletal Phenotypes in Murine Models of Osteomalacia

JBMR Plus, Volume 7, Issue 1, January 2023., 2023
ABSTRACT Hypophosphatasia (HPP), caused by loss‐of‐function mutations in the ALPL gene encoding tissue‐nonspecific alkaline phosphatase (TNAP), is characterized by skeletal and dental hypomineralization that can vary in severity from life‐threatening to milder manifestations only in adulthood.
Flavia Amadeu de Oliveira, Fatma F. Mohamed, Yuka Kinoshita, Sonoko Narisawa, Colin Farquharson, Koichi Miyake, Brian L Foster, Jose Luis Millan   +7 more
wiley   +1 more source

BAREB: A Bayesian repulsive biclustering model for periodontal data [PDF]

arXiv, 2019
Preventing periodontal diseases (PD) and maintaining the structure and function of teeth are important goals for personal oral care. To understand the heterogeneity in patients with diverse PD patterns, we develop BAREB, a Bayesian repulsive biclustering method that can simultaneously cluster the PD patients and their tooth sites after taking the ...
arxiv  

Optimization of quantitative polymerase chain reactions for detection and quantification of eight periodontal bacterial pathogens [PDF]

, 2012
BACKGROUND: The aim of this study was to optimize quantitative (real-time) polymerase chain reaction (qPCR) assays for 8 major periodontal pathogens, i.e.
Cosyn, Jan, De Bruyn, Hugo, Decat, Ellen, Deschaght, Pieter, Miremadi, Seyed Reza, Saerens, Bart, Van Mechelen, Els, Vaneechoutte, Mario, Vermeulen, Stefan   +8 more
core   +1 more source

Roles of Oral Bacteria in Cardiovascular Diseases — From Molecular Mechanisms to Clinical Cases: Treatment of Periodontal Disease Regarded as Biofilm Infection: Systemic Administration of Azithromycin

Journal of Pharmacological Sciences, 2010
Periodontal disease as a biofilm infectious disease is considered. Periodontal disease– associated bacteria formed biofilm in periodontal pockets or on the surface of cementum.
Pao-Li Wang
doaj