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Periodontal Ligament Stem Cells: Regenerative Potency in Periodontium.

Stem Cells and Development, 2019
Periodontium is consisted of root cementum, bone lining the tooth socket, gingiva facing the tooth, and periodontal ligament (PDL). Its primary functions are support of the tooth and protection of tooth, nerve, and blood vessels from injury by mechanical
Atsushi Tomokiyo, Naohisa Wada, H. Maeda
semanticscholar   +1 more source

Periodontal Ligament Stem Cells: Current Knowledge and Future Perspectives.

Stem Cells and Development, 2019
Teeth represent a fascinating area of study in regenerative medicine, because of their unique and complex developmental origin. Several types of mesenchymal stem cells (MSCs) have been characterized in the oral cavity, and those derived from the ...
O. Trubiani   +7 more
semanticscholar   +1 more source

Sequential application of bFGF and BMP-2 facilitates osteogenic differentiation of human periodontal ligament stem cells.

Journal of Periodontal Research, 2019
BACKGROUND AND OBJECTIVES Basic fibroblast growth factor (bFGF) promotes cells proliferation and chemotaxis and maintains stemness while inhibits mineralized nodule formation.
W. Kang   +5 more
semanticscholar   +1 more source

Numerical simulation of hydro-mechanical coupling of periodontal ligament

Proceedings of the Institution of mechanical engineers. Part H, journal of engineering in medicine, 2019
Orthodontic tooth movement in the alveolar bone is due to the mechanical response of periodontal ligament to applied forces. Definition of a proper constitutive model of the periodontal ligament to investigate its response to orthodontic loading is ...
M. Ashrafi   +3 more
semanticscholar   +1 more source

Spheroid culture enhances osteogenic potential of periodontal ligament mesenchymal stem cells

Journal of Periodontal Research, 2018
OBJECTIVE AND BACKGROUND Human periodontal ligament mesenchymal stem cells (hPDLMSCs) are reported to be responsible for homeostasis and regeneration of periodontal tissue.
Y. Moritani   +10 more
semanticscholar   +1 more source

Upregulation of long noncoding RNA MEG3 inhibits the osteogenic differentiation of periodontal ligament cells

Journal of Cellular Physiology, 2018
This study aims to discuss long noncoding RNA (lncRNA) maternally expressed gene 3 (MEG3) function of regulating osteogenesis in human periodontal ligament cells (hPDLCs).
Yi Liu   +9 more
semanticscholar   +1 more source

Changes in characteristics of periodontal ligament stem cells in spheroid culture.

Journal of Periodontal Research, 2018
OBJECTIVES The periodontal ligament (PDL) has important roles in maintaining homeostasis, wound healing, and regeneration of periodontal tissues by supplying stem/progenitor cells. Periodontal ligament stem cells (PDLSCs) have mesenchymal stem cell (MSC)-
K. Iwasaki   +4 more
semanticscholar   +1 more source

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