Results 261 to 270 of about 62,317 (341)

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Treg cell-derived exosomal miR-21 promotes osteogenic differentiation of periodontal ligament stem cells. [PDF]

BMC Oral Health
Xia Y, Jiang H, Wang C, Liu Z, Gao H, Yu JF, Yang N, Liang L.   +7 more
europepmc   +1 more source

Apoptosis and caspase-3 activity in isolated fetal rat lung cells, human A549 cells and rat periodontal ligament fibroblasts following exposure to cigarette smoke extract

, 2012
Asra Ahmed
openalex   +1 more source

Herpesvirus Simplex Virus‐1 Exploits Inflammation to Infect Periodontal Stem Cells and Disrupt Lineage Commitment

Journal of Periodontal Research, EarlyView.
HSV‐1 infects oral mesenchymal stem cells both in vitro and in vivo to dysregulate their lineage commitment. An inflamed gingival environment increases susceptibility to HSV‐1 infection, which further elevates proinflammatory cytokine levels and exacerbates alveolar bone loss.
Araceli Valverde, Raza Ali Naqvi, Yinghua Chen, Alireza Moshaverinia, Anne George, Deepak Shukla, Gloria Martinez, Gabriella Chapa, Salvador Nares, Afsar R. Naqvi   +9 more
wiley   +1 more source

Mechanosensitive Yes-Associated Protein/TAZ-cGAS-STING Axis Induces Periodontal Ligament Fibroblasts Senescence and Mediates Compression-Induced Root Resorption. [PDF]

Int Dent J
Wu Z, Bao S, Chen Q, Lu X, Guan G, Song R, Chen Q, Chen X.   +7 more
europepmc   +1 more source

Inflammation Affects the Osteogenic Differentiation of Aged Periodontal Ligament Cells via NF‐κB/FOXO3a/c‐JUN Signalling

Journal of Periodontal Research, EarlyView.
NF‐κB/FOXO3a/c‐JUN pathway plays a crucial role in osteogenic. Differentiation of aged PDLCs in an inflammatory microenvironment, although the mechanisms of this pathway differ in cellular ageing and pathological inflammation. ABSTRACT Aim This study aims to investigate the effect of inflammation on the senescence phenotype and osteogenic capacity of ...
Luying Zhu, Zhongyuan Tang, Renjie Hu, Yaxin Li, Xuan Li, Min Gu, Yanqi Yang   +6 more
wiley   +1 more source

Isobutyric Acid Regulates Gelatinase Secretion by Human Periodontal Ligament Stem Cells Via NF-κB Signalling. [PDF]

Int Dent J
Tu Y, Fu X, Ning X, Zheng H, Zhang L, Guo Q, Huang M, Cao H, Chen H, Jia Y, Duan M, Liu Y, Pi C, Ren B, Liu C, Xie J.   +15 more
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Piezo1 participates in the tension-driven osteogenic differentiation of periodontal ligament stem cells. [PDF]

BMC Oral Health
Du Y, Zheng J, Xu B, Peng C, Yang K.
europepmc   +1 more source

Histological Outcomes of Root Coverage Procedures: A Systematic Review With Meta‐Analysis

Journal of Periodontal Research, EarlyView.
This systematic review summarizes the current preclinical and clinical evidence for the histological outcomes of root coverage procedures, while also highlighting limitations of existing data, its implications for clinical practice, and suggestions for future research.
Siddharth Shanbhag, Ida Haukåen Stødle, Stein Atle Lie, Mariano Sanz, Anders Verket   +4 more
wiley   +1 more source