Results 171 to 180 of about 1,561,909 (341)

Risk Factors for Implant Failure and Peri‐Implantitis: A Retrospective Cohort Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This retrospective cohort study evaluated patient‐, implant‐, site‐, procedural‐, biological‐, and prosthesis/mechanics‐related factors associated with early and late implant failure and peri‐implantitis. Material and Methods Electronic health record data from a university center were analyzed.
Nathalia Vilela, Bruno C. V. Gurgel, Hélio D. P. da Silva, Claudio M. Pannuti, Poliana M. Duarte   +4 more
wiley   +1 more source

Self-cascade oxygen-generating hydrogel/nanofibrous membrane composites restore periodontal microenvironment homeostasis

Journal of Nanobiotechnology
The hypoxic environment of deep periodontal pockets favors the thriving of anaerobic microbes, leading to dysbiosis, tissue destruction, and treatment resistance.
Ye Liang, Fan Yang, Jun Kang, Zijun Chen, Ting Zou, Shaohua Ge, Chengfei Zhang   +6 more
doaj   +1 more source

Calvarial Bone Channels and a Putative Craniomaxillary–Brain Interface in Central Nervous System Immunity

Med Research, EarlyView.
Ziwen Sheng, Yulong Zhang, Hao Wang, Wenyu Zhen, Youming Zhu, Haitao Wang, Hengguo Zhang   +6 more
wiley   +1 more source

Premature Occlusal Contacts Induce MRONJ in Osseointegrated Dental Implants: An Experimental In Vivo Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives Medication‐related osteonecrosis of the jaw (MRONJ) is a debilitating condition associated with antiresorptive agents (ARAs) and can occur around well‐osseointegrated dental implants. Although implant presence–triggered osteonecrosis (IPTO) has been primarily linked to bacteria‐related peri‐implantitis, whether occlusal trauma ...
Eun‐Bin Bae, Ahana Goswami, Jun Yaung, Soo Yeon Kim, Sherry S. Baik, Kaylyn A. Yu, Chan Park, Jung‐Bo Huh, Jae‐Young Kim, Christine Y. Hong, Sol Kim, Reuben H. Kim   +11 more
wiley   +1 more source

Selective Inhibition of the Periodontal Pathogen Porphyromonas gingivalis by Third-Generation Zafirlukast Derivatives. [PDF]

J Med Chem, 2022
Howard KC, Garneau-Tsodikova S.
europepmc   +1 more source

Periodontitis‐Associated Circulating EVs Promote Colorectal Cancer Progression via Carnosine‐Mediated Acidosis Adaptation

Cell Proliferation, EarlyView.
This study identifies a link between periodontitis and CRC progression mediated by carnosine‐enriched circulating EVs. These EVs target the intestine and elevate tumour cell intracellular pH (pHi), which rescues lysosomal function. This process drives a transition from dysfunctional lysosomes to functional ones, promoting a high malignancy phenotype in
Ruoyi Wu, Zihan Cai, Hualing Sun, Haikun Yu, Bicheng Zhang, Chi Zhang, Yi Fan, Xiaoxuan Zhu, Yueqi Ni, Yu Cui, Kaixin Wang, Zhe Li, Xinyi Zhou, Qing He, Yanru Wu, Yufeng Zhang   +15 more
wiley   +1 more source

Targeting CKIP‐1 for Disease Therapy: Cellular Functions, Molecular Networks, and Clinical Potential

Cell Proliferation, EarlyView.
CKIP‐1, as a scaffold protein with special structural domains, treats related diseases through multiple emerging targeted technologies.
Xin Huang, Shijie Lv, Lejia Li, Jirong Xie, Zhengguo Cao   +4 more
wiley   +1 more source

Neutrophil Transcriptional Deregulation by the Periodontal Pathogen Fusobacterium nucleatum in Gastric Cancer: A Bioinformatic Study. [PDF]

Dis Markers, 2022
Zhou T, Meng X, Wang D, Fu W, Li X.
europepmc   +1 more source

Magnesium Enhances Immune Clearance of P. gingivalis in Macrophages by Suppressing MCU‐Mediated Mitochondrial Calcium Overload

Cell Proliferation, EarlyView.
Magnesium restores macrophage clearance of P. gingivalis by inhibiting MCU‐mediated calcium overload. P. gingivalis is mainly phagocytosed by macrophages but escapes intracellular clearance via MCU‐mediated mitochondrial and cytosolic Ca2+ overload in periodontitis. The persistent P.
Dao‐Kun Deng, Meng‐Jie Su, Min‐Yi Zhang, Yu‐Jie Tan, Wenyao Kongling, Hong‐Yu Wang, Mei Xu, Shi‐Yu Liu, Xiao‐Tao He, Fa‐Ming Chen, Bei‐Min Tian, Xuan Li   +11 more
wiley   +1 more source

Persister Cell Formation and Elevated lsrA and lsrC Gene Expression upon Hydrogen Peroxide Exposure in a Periodontal Pathogen Aggregatibacter actinomycetemcomitans. [PDF]

Microorganisms, 2023
Nakamura Y, Watanabe K, Yoshioka Y, Ariyoshi W, Yamasaki R.   +4 more
europepmc   +1 more source