The aim of this SR was to investigate the risk of metabolic syndrome (MetS) and its single components in individuals with or without periodontitis/edentulism. Within the limits of this SR, periodontitis was associated with one or more new MetS components and the association may be higher for severe periodontitis.
Luigi Barbato +6 more
wiley +1 more source
Molecular Detection of <i>Aggregatibacter actinomycetemcometans</i> and <i>Porphyromonas gingivalis</i> in Children with Cleft Lip and Palate. [PDF]
Hanoon SA +6 more
europepmc +1 more source
Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw +4 more
wiley +1 more source
Natural Bioactive Agents as Adjunctive Candidates in Periodontitis: Mechanistic Links to Cardiovascular Disease and Translational Challenges. [PDF]
Reytor-González C +4 more
europepmc +1 more source
Periodontitis and Rheumatoid Arthritis—Mechanistic Evidence
Periodontitis and rheumatoid arthritis are linked via the two‐hit model whereby early periodontal inflammation can lead to autoantibody production capable of interacting with inflamed synovial tissues. Subsequent systemic inflammation can exacerbate the periodontal inflammatory response and bacterial dysbiosis leading to further autoantibody production
Mark Bartold +2 more
wiley +1 more source
A Synbiotic for the Oral-Nasal Gateway: The Mechanistic Rationale, Pathogen-Targeting Profile, and Implications for Gut and Pulmonary Health. [PDF]
Peldyak JN +4 more
europepmc +1 more source
Porphyromonas gingivalis as a keystone pathogen in systemic diseases. [PDF]
Mayer Y, Matanes D, Shibli JA.
europepmc +1 more source
Evolution, disciplinary integration, and frontiers of multi-omics and single-cell technologies in periodontology: a bibliometric analysis (2000-2025) with an early-2026 frontier update. [PDF]
Li R +9 more
europepmc +1 more source
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Intersection between macrophages and periodontal pathogens in periodontitis
Journal of Leukocyte Biology, 2021AbstractPeriodontitis is a chronic infectious disease characterized by loss of periodontal attachment and resorption of alveolar bone. Dysregulated oral microbial community is the initial factor of periodontitis and causes excessive infiltration of immune cells in periodontal tissues.
Wenzhe, Wang +3 more
openaire +2 more sources

