Results 151 to 160 of about 24,844 (245)

Alternative Polyadenylation Drives Runaway Pro‐Inflammatory Macrophages in Periodontitis by Enabling Escape From miRNA Repression

Cell Proliferation, EarlyView.
APA‐Guided Therapeutic miRNA Selection for Periodontitis. ABSTRACT Periodontitis is a chronic inflammatory disease driven by a dysregulated host immune response, in which macrophage‐mediated inflammation shifts from protective to pathological. While monocyte‐derived macrophages (MDMs) are known to adopt a destructive, M1‐like pro‐inflammatory phenotype,
Jing Zhang, Yilong Zhao, Jiaru Deng, Shuyuan Qu, Yiyi Zhou, Qin Zhao, Yufeng Zhang   +6 more
wiley   +1 more source

Post-translational modifications in the oral microenvironment: Stem cell regulation from periodontal regeneration to oral cancer therapy. [PDF]

World J Stem Cells
Liu W, Yang YY, Shi ZJ.
europepmc   +1 more source

Hypoxia Exacerbates Periapical Periodontitis‐Associated Pathological Bone Loss via the Hypoxia‐Inducible Factor‐2α‐Calmodulin‐Dependent Protein Kinase IV Axis

Cell Proliferation, EarlyView.
Hypoxia exposure activates HIF‐2α, which binds to the Camk4 promoter to enhance RANKL‐mediated osteoclast differentiation, leading to aggravated alveolar bone resorption in periapical periodontitis. ABSTRACT Periapical periodontitis is one of the most common inflammatory bone destructive diseases. Epidemiological evidence suggests that hypoxia exposure,
Kang Gao, Yifan Xu, Haoran Du, Zixiao Li, Xiaochen Fang, Minghui Wang, Jia Liu, Xu Zha, Xianglong Han, Weihua Guo, Xicheng Liu, Jian Zhou   +11 more
wiley   +1 more source

Long term clinical results of intrabony defects treated with periodontal regeneration. A retrospective analysis based on composite outcome measure. [PDF]

Clin Oral Investig
Blasi A, Mauriello L, Iorio-Siciliano V, Pezzella V, Isola G, Ramaglia L.   +5 more
europepmc   +1 more source

Application Strategies of Bone Marrow Mesenchymal Stromal Cells in Bone‐Related Diseases

Cell Proliferation, EarlyView.
Engineered BMSCs and vesicles enhance therapy effects for bone diseases via multi‐strategic approaches. ABSTRACT Bone‐related diseases (e.g., osteoporosis, osteoarthritis and fractures) exhibit a rising global incidence, imposing significant burdens on both quality of life and healthcare systems.
Xuemei Long, Dan Tan, Qianke Tao, Qiaonan Ye, Luwen Ye, Qing Li, Jingang Xiao   +6 more
wiley   +1 more source

Tannic Acid-Enhanced Gelatin-Based Composite Hydrogel as a Candidate for Canine Periodontal Regeneration. [PDF]

Gels
Pinho LC, Ferreira M, Graça A, Marto J, Colaço B, Fernandes MH, Santos C.   +6 more
europepmc   +1 more source

Physicochemical and remineralisation properties of calcium silicate and glass ionomer cements applied in simulated caries‐affected dentine

European Journal of Oral Sciences, EarlyView.
Abstract Calcium silicate‐based and glass ionomer cements are often used in caries‐affected dentine. This study investigated the remineralising and physicochemical properties of two calcium silicates and a glass ionomer cement. Human molars with Class I cavities were subjected to pH cycling to simulate caries lesions.
Monika Lukomska‐Szymanska, Mateusz Radwanski, Stella Helen Constantinidou, Augusto R. Elias Boneta, Umer Daood, Kharouf Naji, Filippo Cardinali, Salvatore Sauro   +7 more
wiley   +1 more source

Collagen Formulation in Xenogeneic Bone Substitutes Influences Cellular Responses in Periodontal Regeneration: An In Vitro Study. [PDF]

Biomimetics (Basel)
Pelaez-Cruz P, López Jornet P, Pons-Fuster E.   +2 more
europepmc   +1 more source

Therapeutic potential of mesenchymal stem cells in peripheral nerve injuries in horses

Equine Veterinary Education, EarlyView.
Summary Peripheral nerve injuries (PNI) in horses represent a significant clinical challenge, frequently associated with functional deficits and reduced athletic performance. Conventional therapeutic approaches, primarily based on anti‐inflammatory treatments and rehabilitation, offer limited efficacy, driving the search for innovative alternatives. In
L. V. de Oliveira Ferreira, R. Martins Amorim   +1 more
wiley   +1 more source

Effect of root surface conditioning agents for enhancing periodontal regeneration. [PDF]

Bioinformation
Tripathi KP, Mishra R, Choubey V, Singh S, Goswami Y, Aglawe A.   +5 more
europepmc   +1 more source