Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan +12 more
wiley +1 more source
Early Wound Healing Score: a system to evaluate the early healing of periodontal soft tissue wounds [PDF]
Purpose: Numerous indices have been proposed to analyse wound healing in oral soft tissues, but each has specific shortcomings. A new method of analysis, the Early Wound Healing Score (EHS), was evaluated in the present study.
Aghazada, Rustam +4 more
core +1 more source
Osteoporosis and Periodontitis [PDF]
Osteoporosis and periodontitis are both diseases characterized by bone resorption. Osteoporosis features systemic degenerative bone loss that leads to loss of skeletal cancellous microstructure and subsequent fracture, whereas periodontitis involves local inflammatory bone loss, following an infectious breach of the alveolar cortical bone, and it may ...
Laurie K. McCauley, Chin-Wei Jeff Wang
openaire +3 more sources
Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng +10 more
wiley +1 more source
Embracing personalized medicine in dentistry
Aim: The aim of this systematic review was to evaluate the number of articles in the area of personalized medicine specific to dentistry. Materials and Methods: Electronic search using three databases was performed using PubMed, Embase, and Scopus search.
Manchala Sesha Reddy +2 more
doaj +1 more source
Oral health-related quality of life of institutionalized elderly in Serbia [PDF]
Background/Aim. Elderly residents in nursing homes have a great risk of periodontal and tooth diseases. Improving oral health can also improve residents’ general health and quality of life.
Petrović Miloš +3 more
doaj +1 more source
Trends and Racial/Ethnic Disparities in Antibiotic Prescribing Practices of Dentists in The United States [PDF]
Objective The aim of this study was to examine trends and racial/ethnic disparities in antibiotic prescribing practices of dentists in the United States. Methods The US Medical Expenditure Panel Survey data for 1996‐2013 was analyzed.
Okunseri, Christopher +4 more
core +1 more source
Bone loss in implants placed at subcrestal and crestal level: A systematic review and meta-analysis [PDF]
Background: To assess differences in marginal bone loss in implants placed at subcrestal versus crestal level. Methods: An electronic and a manual research of articles written in English from Jaunary 2010 to January 2018 was performed by two independent ...
López López, José +2 more
core +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Cell Calcification Models and Their Implications for Medicine and Biomaterial Research
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter +5 more
wiley +1 more source

